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Registry Following Adults with Malignant Hypertension Across Several Centers

Builds a database of adults with malignant hypertension to study the disease over time.

Plain-language title generated from the registry record
Registry title: A New Breath for Malignant Hypertension: Implementation of the HAMA Cohort

Key facts

Where
Annecy, Bayonne, Bobigny, Bordeaux, Chalon-sur-Saône, Chambéry, Clermont-Ferrand, Créteil, Dinard, Grenoble, Haguenau, Le Mans, Libourne, Lille, Marseille, Martigues, Montpellier, Nantes, Paris, Pau, Pitres, Poitiers, Rennes, Rouen, Saint-Denis, Saint-Etienne, Saint-Nazaire, Strasbourg, Toulouse, Tours, and Valenciennes, FranceSee the 36 sites

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The registry is looking for adults with malignant hypertension: very high blood pressure with serious damage in the body.

Age
18 years or older
Sex
All sexes
Disease stage
Blood pressure above 180/110 with severe hypertensive retinopathy (eye damage), or blood pressure above 180/110 with acute damage of 3 target organs.

Main reasons for not taking part

  • Younger than 18 years
  • People who cannot freely give consent
  • People who refuse to take part
  • People on dialysis

Read by machine on 12 November 2026.

Where in France

  • CH d'ANNECYAnnecy, FranceContact: Sandra JOST TURILLOTTaking people
  • CH de la côte BasqueBayonne, FranceContact: Adeline Marie LACRAZTaking people
  • Avicenne APHPBobigny, FranceContact: Marilucy LOPEZ SUBLETTaking people
  • CHU - Hôpital St AndréBordeaux, FranceContact: Philippe GOSSETaking people
  • CH de Chalon sur SaôneChalon-sur-Saône, FranceContact: Maxime FAYARDTaking people
  • CH MétropoleChambéry, FranceContact: Stéphane BALLYTaking people
  • CHU de Clermont-FerrandClermont-Ferrand, FranceContact: Carole PhilipponneTaking people
  • Hopital Henri MondorCréteil, FranceContact: Khalil El KAROUITaking people
  • CH de DinardDinard, FranceContact: Thierry DENOLLETaking people
  • CHU MichallonGrenoble, FranceContact: Olivier ORMEZZANOTaking people
  • hôpital de HaguenauHaguenau, FranceContact: Yves DIMITROVTaking people
  • Pôle Santé SudLe Mans, FranceContact: Christophe BACHELETTaking people
  • CH de LibourneLibourne, FranceContact: Adrien KELLERTaking people
  • CHRU de LilleLille, FranceContact: Pascal DELSARTTaking people
  • Clinique Vert CoteauMarseille, FranceContact: Michèle ESCANDETaking people
  • Hôpital de la ConceptionMarseille, FranceContact: Thomas ROBERTTaking people
  • CH MartiguesMartigues, FranceContact: Christophe BOUAKATaking people
  • CHU de MontellierMontpellier, FranceContact: Pierre FESLERTaking people
  • CHU - Hôpital LaennecNantes, FranceContact: Guillaume LAMIRAULTTaking people
  • APHP BichatParis, FranceContact: Emmenuelle VIDAL PETIOTTaking people
  • Fondation Adolphe de RothschildParis, FranceContact: Benjamin MAIERTaking people
  • Hôpital Européen Georges PompidouParis, FranceContact: Aurélien LORTHIOIRTaking people
  • Hopital Saint JosephParis, FranceContact: Yara HANON - ANTAKLYTaking people
  • Hôpital TenonParis, FranceContact: Laurent MESNARDTaking people
  • CH de PauPau, FranceContact: Romain BoustreauTaking people
  • CHU de Pointe à PitrePitres, FranceContact: Valérie ALOPH GALANTINENot yet recruiting
  • CHU de PoitiersPoitiers, FranceContact: Benoit LEQUEUXTaking people
  • CHU de RennesRennes, FranceContact: Caroline DOURMAPTaking people
  • CHU de RouenRouen, FranceContact: Dominique GUERROTTaking people
  • Clinique sainte ClotildeSaint-Denis, FranceContact: Lucas MORLONTaking people
  • CHU de St EtienneSaint-Etienne, FranceContact: Miriana DINICTaking people
  • CH de St NazaireSaint-Nazaire, FranceContact: Sylvie LE COZTaking people
  • CHU de StrasbourgStrasbourg, FranceContact: Dominique STEPHANTaking people
  • CHU de Toulouse RangueilToulouse, FranceContact: Béatrice DULY-BOUHANICKTaking people
  • CHU de ToursTours, FranceContact: Jean Michel HALIMITaking people
  • CH de ValenciennesValenciennes, FranceContact: Claire CARTERYTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Centre Hospitalier de PAU
Trial code
NCT03755726
Record updated
23 March 2026
Original description
This registry aims to provide the first prospective, multicentric database of patients with malignant hypertension. It will allow to assess modern epidemiology of the disease, diversity of current management and care pathway, to deepen our pathophysiological knowledges, to modernize the definition of this form of hypertension and its diagnostic criteria. The network that will emerge will finally lead to the opportunity of setting up therapeutic trials and establishing recommendations based on solid scientific evidence.Read full original descriptionShow less

A New Breath for Malignant Hypertension: Implementation of the HAMA Cohort

This registry aims to provide the first prospective, multicentric database of patients with malignant hypertension. It will allow to assess modern epidemiology of the disease, diversity of current management and care pathway, to deepen our pathophysiological knowledges, to modernize the definition of this form of hypertension and its diagnostic criteria. The network that will emerge will finally lead to the opportunity of setting up therapeutic trials and establishing recommendations based on solid scientific evidence.

Inclusion: Malignant hypertension according to the classic definition (Severe hypertension, above 180/110 associated with severe hypertensive retinopathy); Severe hypertension (above 180/110) associated with acute damage of 3 target organ due to high blood pressure.

Exclusion: Age < 18 years old; Patients who cannot freely give their consent, or patients who refuse to participate; Dialysis.

ClinicalTrials.gov NCT03755726