Washed Microbiota Transplantation for Tourette's Syndrome
Key facts
- Where
- Nanjing, ChinaSee the 2 sites
- Phase
- Phase 1
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 17 years old?
Source: NCT03764748, who can take part
Where in China
- Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical UniversityNanjing, ChinaContact: Faming Zhang, PhD,MDTaking people
- Sir Run Run Hospital of Nanjing Medical UniversityNanjing, ChinaContact: Faming Zhang, MD, PhDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- The Second Hospital of Nanjing Medical University
- Trial code
- NCT03764748
- Record updated
- 19 August 2024
- Original description
This study aimed to evaluate the efficacy of washed microbiota transplantation in the treatment of Tourette's syndrome (TS).Read full original descriptionShow less
Efficacy and Safety of Washed Microbiota Transplantation for Tourette's Syndrome
This study aimed to evaluate the efficacy of washed microbiota transplantation in the treatment of Tourette's syndrome (TS).
Inclusion: Patients were aged 6 to 17 years (inclusive); Met the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria for TS; Had a Yale Global Tic Severity Scale-Total Tic Score (YGTSS-TTS) of at least 20 at screening and baseline; Underwent WMT.
Exclusion: Medications use affecting gut microbiota such as antibiotics and probiotics three months before WMT; Complicated with certain brain disease, including tumor,injury,cerebrovascular disease; Complicated with other severe disease, including cancers, organ failure, heart diseases; Stereotypy associated with autism spectrum disorder; With a confirmed diagnosis of psychiatric diseases, such as bipolar disorders; schizophrenia and major depressive disorders; Clinically significant obsessive-compulsive disorder at baseline considered to be the primary cause of impairment at baseline; Other neurologic disorders other than TS that could influence the evaluation of tics.