A Multidisciplinary Intervention in Total Knee Arthroplasty
Key facts
- Who runs it
- Lovisenberg Diakonale Hospital
- Where
- Norway3 sites in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 282 people enrolled
- Started
- 28 Aug 2019
- Ended
- 30 Apr 2026
- Type of study
- Interventional, 3 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Osteoarthritis education, exercise and CBT
- Total Knee Arthroplasty
- Record updated
- 11 August 2026
Who can take part
- Age
- 18 years to 79 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Scheduled for TKA for OA at Lovisenberg, Oslo; Martina Hansen, Bærum, or Coastal Hospital Hagevik, Bergen
- Age 18 - 79 years
- ASA grade 1-3
- KL grade 3 or 4
- BMI<40
- Able to read and write in Norwegian
Who cannot take part
- Previously undergone uni or patellofemoral prosthesis in the index knee
- Large axis deviation or instability requiring use of hinged implants
- Scheduled for unicompartmental arthroplasty or revision surgery
- Diagnosis of dementia or sero-positive rheumatic disease
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The purpose of this study is to investigate the effectiveness of cognitive behavioral therapy delivered as an e-therapy program, combined with physical exercise delivered by physiotherapists, for patients on waiting list for total knee arthroplasty. The patients will be randomized to either 1) a non-surgical program consisting of web-based cognitive behavioral therapy combined with physiotherapy, 2) total knee arthroplasty (TKA) surgery followed by web-based cognitive behavioral therapy combined with physiotherapy, or 3) a control group who undergo TKA followed by standard physiotherapy.
The 3 groups in the trial
- Non-surgical groupTreatment being tested
Osteoarthritis education, exercise and eCBT
Treatment: Osteoarthritis education, exercise and CBT
- Combined groupTreatment being tested
Total knee arthroplasty + osteoarthritis education, exercise and eCBT
Treatment: Osteoarthritis education, exercise and CBT and Total Knee Arthroplasty
- Surgery only (standard care)Existing treatment, for comparison
Total knee arthroplasty + standard physiotherapy
Treatment: Total Knee Arthroplasty
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Multidisciplinary Intervention in Total Knee Arthroplasty - a Multicenter, Randomized Controlled Trial in OA Patients (The MultiKnee Trial)
- Publications
- Record updated
- 11 August 2026