Stitching the ovary after removing ovarian endometrioma cysts
Compares stitching versus not stitching the ovary after cyst removal in women with endometriomas.
Plain-language title generated from the registry record
Registry title: Suture of the Ovary After Enucleation of Ovarian Endometrioma
Key facts
- Where
- Varese, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 35 years old?
Source: NCT03788720, who can take part
Where in Italy
- "Filippo Del Ponte" HospitalVarese, ItalyNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Università degli Studi dell'Insubria
- Trial code
- NCT03788720
- Record updated
- 29 April 2021
- Original description
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity.Read full original descriptionShow less
Comparison Between Suture of the Ovary Versus no Suture After Enucleation of Ovarian Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity.
According to the most updated guidelines of the European Society of Human Reproduction and Embryology (ESHRE), infertile women with endometriomas smaller than 3 cm should be addressed directly to Assisted Reproduction Technology (ART); conversely, for infertile women with endometriomas larger than 3 cm, enucleation of ovarian endometriomas could be considered in order to improve reproductive outcomes (both spontaneous and ART pregnancy rate).
To date, literature data do not allow to draw a firm conclusion about the best strategy to reduce ovarian damage during enucleation of ovarian endometriomas: in particular, investigators still lack robust evidence in order to choose between suturing the ovary or not after the enucleation.
In this scenario, the aim of our the study will be to compare functional outcomes of the ovary in a group of women undergoing suturing of the ovarian cortex after laparoscopic enucleation of endometriomas (cases) and a group of women undergoing laparoscopic enucleation of endometriomas without subsequent suture of the ovarian cortex.
Inclusion: Women affected by one primary (no recurrent) monolateral ovarian endometrioma, with maximum diameter between 5 and 10 cm, undergoing laparoscopic enucleation by stripping technique; Normal AFC at the enrollment (baseline).
Exclusion: No previous pelvic surgery (even not gynecological); Any other pharmacologic and non pharmacologic treatment in the previous 3 months (wash-out period); Any other disease; Bilateral endometriomas; Deep infiltrating endometriosis.