Fecal Microbiota Transplantation for Ulcerative Colitis
Key facts
- Where
- Guangzhou, ChinaSee the site
- Phase
- Phase 2/3
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT03804931, who can take part
Where in China
- Guangzhou First People's HospitalGuangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Guangzhou First People's Hospital
- Trial code
- NCT03804931
- Record updated
- 15 January 2019
- Original description
Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. Fecal microbiota transplantation has been used for several disease，but the efficacy of ulcerative colitis(UC) by fecal microbiota transplantation needs to be further explored.The investigators propose to determine the efficiency and safety of FMT in patients with ulcerative colitis(UC).Read full original descriptionShow less
Efficacy and Safety of Fecal Microbiota Transplantation for Ulcerative Colitis
Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. Fecal microbiota transplantation has been used for several disease，but the efficacy of ulcerative colitis(UC) by fecal microbiota transplantation needs to be further explored.The investigators propose to determine the efficiency and safety of FMT in patients with ulcerative colitis(UC).
Inclusion: Active, moderate to severe severity (Mayo score more than 6); Safety using history of 5-ASA; Able to undergo endoscopy examination.
Exclusion: Colon cancer or neoplasia in pathophysiology; Other severe diseases (eg: cardiovascular, respiratory, gastroenteral and kidney diseases); Antibiotic using in 7 days; High risk of toxic megacolon.