Observational database tracking chronic diseases, treatments and outcomes over time
Collects real-world patient records on chronic diseases and their treatments in routine care.
Plain-language title generated from the registry record
Registry title: Observational Pharmaco-Epidemiology Research & Analysis
Key facts
- Where
- Durham, United StatesSee the site
Where in United States
- EpividianDurham, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Epividian
- Trial code
- NCT03813862
- Record updated
- 11 September 2026
- Original description
Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of routine patient care, population management and disease management; and 2) the use of the point-of-care observational data from the provider-patient encounter that support realworld medical research and healthcare quality measure assessment. Real-world evaluations of treatments of chronic diseases in the context of comorbid conditions and special populations (minorities, women, mentally ill, and those with addiction) are limited. The purpose of the OPERA database is to help address this unmet need in clinical research.Read full original descriptionShow less
OPERA Longitudinal Observational Database in the Study of Chronic Diseases, Treatments and Outcomes
Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of routine patient care, population management and disease management; and 2) the use of the point-of-care observational data from the provider-patient encounter that support realworld medical research and healthcare quality measure assessment. Real-world evaluations of treatments of chronic diseases in the context of comorbid conditions and special populations (minorities, women, mentally ill, and those with addiction) are limited. The purpose of the OPERA database is to help address this unmet need in clinical research.
Inclusion: Patients who are treated in the practices who enroll and participate in the study; Patients whose treatment is documented in the practice's electronic health record system.
Exclusion: Patients who opt out of OPERA.