Collecting blood samples from adults with hepatitis B to study viral RNA
Collects blood samples from adults with hepatitis B to study viral RNA.
Plain-language title generated from the registry record
Registry title: Creation of a Cohort for the Quantitation and Characterization of Circulating Viral RNAs as a New Biomarker of Hepatitis B Functional Cure.
Key facts
- Where
- Lyon, FranceSee the 3 sites
Where in France
- Department of Hepato-gastroenterology and pediatric nutrition - Hôpital Femme-Mère EnfantLyon, FranceTaking people
- Hepatology department - Groupement Hospitalier Nord - Hôpital de la Croix-RousseLyon, FranceTaking people
- Hôpital de la Croix-Rousse - Service de maladies infectieuses et tropicalesLyon, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospices Civils de Lyon
- Trial code
- NCT03825458
- Record updated
- 22 May 2026
- Original description
The " CirB-RNA " cohort aims to create a biological collection associated with clinical and biological data from patients with hepatitis B infection. This project is part of a much larger program that aims to characterize and quantify circulating viral RNAs as a possible new biomarker of hepatitis B functional cure.Read full original descriptionShow less
Creation of a Cohort for the Quantitation and Characterization of Circulating Viral RNAs as a New Biomarker of Hepatitis B Functional Cure.
The " CirB-RNA " cohort aims to create a biological collection associated with clinical and biological data from patients with hepatitis B infection. This project is part of a much larger program that aims to characterize and quantify circulating viral RNAs as a possible new biomarker of hepatitis B functional cure.
Inclusion: Adults patients and minor children over 6 years of age (in Lyon) with acute or chronic hepatitis B or presenting with HBsAg loss (with/without HBs seroconversion). (Co-infected patients with HDV and/or HCV and/or HIV are eligible); Patients requiring blood sampling for medical care at the time of the medical appointment; Informed patients who do not refuse to participate; Persons not affiliated to a social security scheme and persons receiving medical assistance from the state may be asked to participate in the study.
Exclusion: Patients participating at the time of the inclusion to an interventional trial evaluating a drug likely to interfere with this study; Children less than 6 years old (in Lyon); Persons deprived of their liberty by a judicial or administrative decision; Adults who are subject to a legal protection measure.