Oesophagectomy and Chest Wall and Respiratory Function
Reason given: Study closed before the planned recruitment target was reached because the study period ended before full recruitment could be completed. Recruitment ceased at study closure and data collection was completed for enrolled participants.
Key facts
- Where
- London, United KingdomSee the site
Where in United Kingdom
- Charing Cross HospitalLondon, United KingdomNo longer taking part
Trial details
- Who runs it
- Imperial College London
- Trial code
- NCT03835273
- Record updated
- 23 July 2026
- Original description
Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%). Minimally invasive approach through keyhole surgery has been shown to reduce pulmonary infections by 20%. Enhanced recovery programmes are evidence-based protocols, developed to achieve early recovery after surgery with early mobilisation and chest physiotherapy and have been shown to reduce pulmonary complication rates as well. The investigators intend to objectively measure chest wall movement using 3D motion capture system as well as a wearable measurement system to monitor chest wall movement.Read full original descriptionShow less
Changes in Respiratory Function and Chest Wall Movement Following Oesophagectomy
Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%). Minimally invasive approach through keyhole surgery has been shown to reduce pulmonary infections by 20%. Enhanced recovery programmes are evidence-based protocols, developed to achieve early recovery after surgery with early mobilisation and chest physiotherapy and have been shown to reduce pulmonary complication rates as well. The investigators intend to objectively measure chest wall movement using 3D motion capture system as well as a wearable measurement system to monitor chest wall movement.
Inclusion: Exposure group:; Patients treated more than a year ago with oesophagectomy for oesophageal cancer, by an open approach; Patients able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study; Control group:; Healthy volunteers with no underlying respiratory disease and no history of upper gastrointestinal surgery; Individuals able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study.
Exclusion: Any patient with evidence of cancer recurrence or on-going postoperative complication at more than one year following surgery for oesophageal cancer; Any participant younger than 18 or older than 90 years of age; Any participant who lacks capacity or is unable to provide informed consent; Any pregnant participant; unable to or excluded from performing spirometry or respiratory muscle strength testing (non-invasive testing).