Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Key facts
- Where
- Aberdeen, Aitkin, Alcoa, Allentown, Alton, Ames, Anaconda, Anchorage, Ankeny, Ann Arbor, Arroyo Grande, Ashland, Atlanta, Aurora, Aventura, Baker City, Ballwin, Baltimore, Bardstown, Basking Ridge, Baton Rouge, Beavercreek, Bellevue, Bellingham, Belpre, Bend, Bethesda, Bethlehem, Bettendorf, Billings, Birmingham, Bloomington, Boardman, Boise, Bolivar, Bonne Terre, Boone, Bozeman, Brainerd, Branson, Brighton, Brooklyn, Brownstown, Bryan, Buffalo, Burbank, Burien, Burlington, Burnsville, Burr Ridge, Caldwell, Cambridge, Canton, Cape Girardeau, Carbondale, Caro, Carson City, Carterville, Carthage, Centerville, Centralia, Chanute, Chapel Hill, Charleston, Chelsea, Chicago, Chillicothe, Cincinnati, City of Saint Peters, Clackamas, Clarkston, Clinton Township, Clive, Clovis, Cody, Coeur d'Alene, Colorado Springs, Columbus, Commack, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Covington, Creston, Creve Coeur, Cudahy, Dallas, Danville, Dayton, Dearborn, Decatur, Deer River, Delaware, Denver, Des Moines, Detroit, Detroit Lakes, Dixon, Dodge City, Dublin, Duluth, Durango, East China Township, East Stroudsburg, Eau Claire, Edina, Edmonds, Effingham, El Dorado, Emeryville, Emmett, Enumclaw, Erie, Eureka, Everett, Fairway, Fargo, Farmington, Federal Way, Fergus Falls, Findlay, Flint, Fort Dodge, Fort Lauderdale, Fort Smith, Fort Worth, Fosston, Franklin, Frederick, Fridley, Fruitland, Gahanna, Galesburg, Garden City, Germantown, Grafton, Grand Island, Great Bend, Great Falls, Green Bay, Greenbrae, Greensburg, Greenville, Grosse Pointe Woods, Grove City, Harrison, Hays, Hazleton, Helena, Henderson, Hendersonville, Hibbing, Homer Glen, Hot Springs, Independence, Iowa City, Issaquah, Jackson, Jamestown, Jefferson, Jefferson City, Jefferson Hills, Johns Creek, Joplin, Kalispell, Kansas City, Kearney, Kenner, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Knoxville, Lacey, Lake Forest, Lake Success, Lakewood, Lancaster, Lansing, Las Vegas, Lawrence, Lawton, Lee's Summit, Lexington, Liberal, Lima, Lincoln, Littleton, Livonia, London, Longmont, Longview, Los Angeles, Louisville, Macomb, Manhattan, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marshalltown, Marshfield, Martinez, Marysville, Mattoon, Maywood, McPherson, Melrose Park, Meridian, Metairie, Miami Beach, Middletown, Milwaukee, Mineola, Minneapolis, Minocqua, Missoula, Monroeville, Monticello, Montvale, Mount Vernon, Mukwonago, N. Huntingdon, Nampa, Nashville, Natrona Heights, New Lenox, New Orleans, New Richmond, New Ulm, New York, Newark, Newberg, Newport Beach, Newton, Novi, O'Fallon, Oak Park, Oakland, Oconomowoc, Oklahoma City, Olathe, Omaha, Ontario, Oregon City, Orland Park, Orlando, Oshkosh, Ottawa, Pahrump, Papillion, Park Rapids, Parker, Parsons, Peabody, Pekin, Peoria, Perrysburg, Peru, Phoenix, Pittsburg, Pittsburgh, Pontiac, Port Huron, Portland, Portsmouth, Post Falls, Poulsbo, Pratt, Princeton, Pueblo, Racine, Redmond, Reno, Renton, Rice Lake, Richardson, Richmond, Robbinsdale, Rochester, Rochester Hills, Rolla, Saginaw, Saint Joseph, Saint Louis Park, Saint Paul, Sainte Genevieve, Salina, San Luis Obispo, Sandpoint, Sandstone, Santa Maria, Scottsdale, Seattle, Sedro-Woolley, Shakopee, Sheboygan, Shelby, Shelton, Shepherdsville, Sheridan, Shiloh, Silverdale, Springfield, St Louis, Sterling Heights, Stevens Point, Stillwater, Sullivan, Summit, Swansea, Syracuse, Tacoma, Tawas City, Toledo, Topeka, Troy, Tucson, Tulsa, Twin Falls, Two Rivers, Uniondale, Urbana, Vancouver, Virginia, Waconia, Walla Walla, Walnut Creek, Warren, Washington, Washington D.C., Waukee, Waukesha, Wauwatosa, Wellington, West Allis, West Bloomfield, West Branch, West Chester, West Des Moines, Westerville, Weston, Westwood, Wexford, Wichita, Willmar, Winchester, Winfield, Woodbury, Wyandotte, Wyoming, Yakima, Yelm, Yorkville, Youngstown, Ypsilanti, and Zanesville, United StatesSee the 581 sites
- Phase
- Phase 2
Where in United States
- Providence Regional Cancer System-AberdeenAberdeen, United StatesNo longer taking part
- Riverwood Healthcare CenterAitkin, United StatesNo longer taking part
- University Cancer Specialists - AlcoaAlcoa, United StatesNo longer taking part
- Lehigh Valley Hospital-Cedar CrestAllentown, United StatesTaking people
- OSF Saint Anthony's Health CenterAlton, United StatesNo longer taking part
- Mary Greeley Medical CenterAmes, United StatesTaking people
- McFarland Clinic - AmesAmes, United StatesTaking people
- Community Hospital of AnacondaAnaconda, United StatesTaking people
- Alaska Breast Care and Surgery LLCAnchorage, United StatesNo longer taking part
- Alaska Oncology and Hematology LLCAnchorage, United StatesNo longer taking part
- Alaska Women's Cancer CareAnchorage, United StatesNo longer taking part
- Anchorage Associates in Radiation MedicineAnchorage, United StatesNo longer taking part
- Anchorage Oncology CentreAnchorage, United StatesNo longer taking part
- Anchorage Radiation Therapy CenterAnchorage, United StatesNo longer taking part
- Katmai Oncology GroupAnchorage, United StatesNo longer taking part
- Providence Alaska Medical CenterAnchorage, United StatesNo longer taking part
- UI Health Care Mission Cancer and Blood - Ankeny ClinicAnkeny, United StatesTaking people
- Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, United StatesTaking people
- Mission Hope Medical Oncology - Arroyo GrandeArroyo Grande, United StatesNo longer taking part
- PCR OncologyArroyo Grande, United StatesNo longer taking part
- Duluth Clinic AshlandAshland, United StatesTaking people
- Northwest Wisconsin Cancer CenterAshland, United StatesNo longer taking part
- Emory University Hospital MidtownAtlanta, United StatesTaking people
- Emory University Hospital/Winship Cancer InstituteAtlanta, United StatesTaking people
- Emory Saint Joseph's HospitalAtlanta, United StatesNo longer taking part
- Rush-Copley Medical CenterAurora, United StatesNo longer taking part
- Mount Sinai Comprehensive Cancer Center at AventuraAventura, United StatesNo longer taking part
- Saint Alphonsus Cancer Care Center-Baker CityBaker City, United StatesNo longer taking part
- Mercy Oncology and Hematology - Clayton-ClarksonBallwin, United StatesNo longer taking part
- Greater Baltimore Medical CenterBaltimore, United StatesNo longer taking part
- CommonSpirit Saint Joseph Hospital - BardstownBardstown, United StatesNo longer taking part
- Memorial Sloan Kettering Basking RidgeBasking Ridge, United StatesTaking people
- Louisiana Hematology Oncology Associates LLCBaton Rouge, United StatesTaking people
- Hematology/Oncology Clinic PLLCBaton Rouge, United StatesNo longer taking part
- Ochsner High GroveBaton Rouge, United StatesNo longer taking part
- Indu and Raj Soin Medical CenterBeavercreek, United StatesNo longer taking part
- Nebraska Medicine-BellevueBellevue, United StatesTaking people
- Overlake Medical CenterBellevue, United StatesNo longer taking part
- PeaceHealth Saint Joseph Medical CenterBellingham, United StatesNo longer taking part
- Strecker Cancer Center-BelpreBelpre, United StatesTaking people
- Saint Charles Health SystemBend, United StatesNo longer taking part
- National Institutes of Health Clinical CenterBethesda, United StatesTaking people
- Lehigh Valley Hospital - MuhlenbergBethlehem, United StatesTaking people
- University of Iowa Healthcare Cancer Services Quad CitiesBettendorf, United StatesTaking people
- Billings Clinic Cancer CenterBillings, United StatesTaking people
- University of Alabama at Birmingham Cancer CenterBirmingham, United StatesTaking people
- Illinois CancerCare-BloomingtonBloomington, United StatesNo longer taking part
- Saint Elizabeth Boardman HospitalBoardman, United StatesNo longer taking part
- Saint Alphonsus Cancer Care Center-BoiseBoise, United StatesTaking people
- Saint Luke's Cancer Institute - BoiseBoise, United StatesNo longer taking part
- Central Care Cancer Center - BolivarBolivar, United StatesNo longer taking part
- Parkland Health Center-Bonne TerreBonne Terre, United StatesNo longer taking part
- McFarland Clinic - BooneBoone, United StatesNo longer taking part
- Bozeman Health Deaconess HospitalBozeman, United StatesTaking people
- Essentia Health Saint Joseph's Medical CenterBrainerd, United StatesNo longer taking part
- Cox Cancer Center BransonBranson, United StatesNo longer taking part
- Trinity Health IHA Medical Group Hematology Oncology - BrightonBrighton, United StatesTaking people
- Trinity Health Medical Center - BrightonBrighton, United StatesTaking people
- Maimonides Medical CenterBrooklyn, United StatesNo longer taking part
- New York-Presbyterian/Brooklyn Methodist HospitalBrooklyn, United StatesNo longer taking part
- Henry Ford Cancer Institute-DownriverBrownstown, United StatesTaking people
- Saint Joseph Regional Cancer CenterBryan, United StatesNo longer taking part
- Roswell Park Cancer InstituteBuffalo, United StatesNo longer taking part
- Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, United StatesNo longer taking part
- Saint Anne HospitalBurien, United StatesNo longer taking part
- Aurora Cancer Care-Southern Lakes VLCCBurlington, United StatesTaking people
- Lahey ClinicBurlington, United StatesTaking people
- Fairview Ridges HospitalBurnsville, United StatesNo longer taking part
- Minnesota Oncology - BurnsvilleBurnsville, United StatesNo longer taking part
- Loyola Center for Health at Burr RidgeBurr Ridge, United StatesNo longer taking part
- Saint Alphonsus Cancer Care Center-CaldwellCaldwell, United StatesTaking people
- Cambridge Medical CenterCambridge, United StatesNo longer taking part
- Trinity Health IHA Medical Group Hematology Oncology - CantonCanton, United StatesTaking people
- Trinity Health Medical Center - CantonCanton, United StatesTaking people
- Illinois CancerCare-CantonCanton, United StatesNo longer taking part
- Saint Francis Medical CenterCape Girardeau, United StatesTaking people
- Mercy Cancer Center - Cape GirardeauCape Girardeau, United StatesNo longer taking part
- Memorial Hospital of CarbondaleCarbondale, United StatesNo longer taking part
- Caro Cancer CenterCaro, United StatesNo longer taking part
- Carson Tahoe Regional Medical CenterCarson City, United StatesNo longer taking part
- SIH Cancer InstituteCarterville, United StatesNo longer taking part
- Illinois CancerCare-CarthageCarthage, United StatesNo longer taking part
- Dayton Physicians LLC-Miami Valley SouthCenterville, United StatesNo longer taking part
- Miami Valley Hospital SouthCenterville, United StatesNo longer taking part
- Providence Regional Cancer System-CentraliaCentralia, United StatesNo longer taking part
- Cancer Center of Kansas - ChanuteChanute, United StatesNo longer taking part
- UNC Lineberger Comprehensive Cancer CenterChapel Hill, United StatesTaking people
- Medical University of South CarolinaCharleston, United StatesTaking people
- Chelsea HospitalChelsea, United StatesTaking people
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea, United StatesTaking people
- Rush MD Anderson Cancer CenterChicago, United StatesTaking people
- University of Chicago Comprehensive Cancer CenterChicago, United StatesTaking people
- Northwestern UniversityChicago, United StatesNo longer taking part
- University of IllinoisChicago, United StatesNo longer taking part
- Adena Regional Medical CenterChillicothe, United StatesTaking people
- Bethesda North HospitalCincinnati, United StatesNo longer taking part
- Good Samaritan Hospital - CincinnatiCincinnati, United StatesNo longer taking part
- Oncology Hematology Care Inc-KenwoodCincinnati, United StatesNo longer taking part
- TriHealth Cancer Institute-AndersonCincinnati, United StatesNo longer taking part
- TriHealth Cancer Institute-WestsideCincinnati, United StatesNo longer taking part
- University of Cincinnati Cancer Center-UC Medical CenterCincinnati, United StatesNo longer taking part
- Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, United StatesTaking people
- Clackamas Radiation Oncology CenterClackamas, United StatesNo longer taking part
- Providence Cancer Institute Clackamas ClinicClackamas, United StatesNo longer taking part
- Hematology Oncology Consultants-ClarkstonClarkston, United StatesTaking people
- Newland Medical Associates-ClarkstonClarkston, United StatesNo longer taking part
- Henry Ford Macomb Hospital-Clinton TownshipClinton Township, United StatesTaking people
- UI Health Care Mission Cancer and Blood - West Des Moines ClinicClive, United StatesTaking people
- Mercy Cancer Center-West LakesClive, United StatesNo longer taking part
- Community Cancer InstituteClovis, United StatesNo longer taking part
- University Oncology AssociatesClovis, United StatesNo longer taking part
- Billings Clinic-CodyCody, United StatesNo longer taking part
- Kootenai Health - Coeur d'AleneCoeur d'Alene, United StatesTaking people
- Penrose-Saint Francis HealthcareColorado Springs, United StatesNo longer taking part
- Rocky Mountain Cancer Centers-PenroseColorado Springs, United StatesNo longer taking part
- Columbus Oncology and Hematology Associates IncColumbus, United StatesTaking people
- Doctors HospitalColumbus, United StatesTaking people
- Grant Medical CenterColumbus, United StatesTaking people
- Mount Carmel East HospitalColumbus, United StatesTaking people
- Mount Carmel Health Center WestColumbus, United StatesTaking people
- Ohio State University Comprehensive Cancer CenterColumbus, United StatesTaking people
- Riverside Methodist HospitalColumbus, United StatesTaking people
- The Mark H Zangmeister CenterColumbus, United StatesTaking people
- Memorial Sloan Kettering CommackCommack, United StatesTaking people
- Mercy HospitalCoon Rapids, United StatesNo longer taking part
- Bay Area HospitalCoos Bay, United StatesNo longer taking part
- Commonwealth Cancer Center-CorbinCorbin, United StatesNo longer taking part
- Alegent Health Mercy HospitalCouncil Bluffs, United StatesNo longer taking part
- Northshore Oncology Associates-CovingtonCovington, United StatesTaking people
- Greater Regional Medical CenterCreston, United StatesNo longer taking part
- Siteman Cancer Center at West County HospitalCreve Coeur, United StatesTaking people
- Aurora Saint Luke's South ShoreCudahy, United StatesNo longer taking part
- UT Southwestern Simmons Cancer Center - RedBirdDallas, United StatesTaking people
- UT Southwestern/Simmons Cancer Center-DallasDallas, United StatesTaking people
- Carle at The RiverfrontDanville, United StatesTaking people
- Dayton Physician LLC - EnglewoodDayton, United StatesNo longer taking part
- Good Samaritan Hospital - DaytonDayton, United StatesNo longer taking part
- Miami Valley HospitalDayton, United StatesNo longer taking part
- Miami Valley Hospital NorthDayton, United StatesNo longer taking part
- Henry Ford Medical Center-FairlaneDearborn, United StatesTaking people
- Cancer Care Specialists of Illinois - DecaturDecatur, United StatesTaking people
- Decatur Memorial HospitalDecatur, United StatesNo longer taking part
- Essentia Health - Deer River ClinicDeer River, United StatesTaking people
- Delaware Health Center-Grady Cancer CenterDelaware, United StatesTaking people
- Grady Memorial HospitalDelaware, United StatesTaking people
- AdventHealth PorterDenver, United StatesNo longer taking part
- Iowa Methodist Medical CenterDes Moines, United StatesTaking people
- Mercy Medical Center - Des MoinesDes Moines, United StatesTaking people
- UI Health Care Mission Cancer and Blood - Des Moines ClinicDes Moines, United StatesTaking people
- UI Health Care Mission Cancer and Blood - Laurel ClinicDes Moines, United StatesTaking people
- Henry Ford Health Saint John HospitalDetroit, United StatesTaking people
- Henry Ford HospitalDetroit, United StatesTaking people
- Essentia Health Saint Mary's - Detroit Lakes ClinicDetroit Lakes, United StatesNo longer taking part
- Illinois CancerCare-DixonDixon, United StatesNo longer taking part
- Cancer Center of Kansas - Dodge CityDodge City, United StatesNo longer taking part
- Dublin Methodist HospitalDublin, United StatesNo longer taking part
- Epic Care-DublinDublin, United StatesNo longer taking part
- Essentia Health Cancer CenterDuluth, United StatesTaking people
- Essentia Health Saint Mary's Medical CenterDuluth, United StatesNo longer taking part
- Miller-Dwan HospitalDuluth, United StatesNo longer taking part
- CommonSpirit Cancer Center MercyDurango, United StatesNo longer taking part
- Mercy Medical CenterDurango, United StatesNo longer taking part
- Henry Ford River District HospitalEast China Township, United StatesTaking people
- Pocono Medical CenterEast Stroudsburg, United StatesTaking people
- Marshfield Medical Center-EC Cancer CenterEau Claire, United StatesTaking people
- Mayo Clinic Health System-Eau Claire ClinicEau Claire, United StatesTaking people
- Fairview Southdale HospitalEdina, United StatesTaking people
- Minnesota Oncology - EdinaEdina, United StatesTaking people
- Swedish Cancer Institute-EdmondsEdmonds, United StatesNo longer taking part
- Carle Physician Group-EffinghamEffingham, United StatesTaking people
- Crossroads Cancer CenterEffingham, United StatesTaking people
- Cancer Center of Kansas - El DoradoEl Dorado, United StatesNo longer taking part
- Bay Area Breast Surgeons IncEmeryville, United StatesNo longer taking part
- Epic Care Partners in Cancer CareEmeryville, United StatesNo longer taking part
- Walter Knox Memorial HospitalEmmett, United StatesNo longer taking part
- Saint Elizabeth HospitalEnumclaw, United StatesNo longer taking part
- UPMC Hillman Cancer Center ErieErie, United StatesTaking people
- Saint Vincent HospitalErie, United StatesNo longer taking part
- Illinois CancerCare-EurekaEureka, United StatesNo longer taking part
- Providence Regional Cancer PartnershipEverett, United StatesNo longer taking part
- University of Kansas Clinical Research CenterFairway, United StatesNo longer taking part
- Essentia Health Cancer Center-South University ClinicFargo, United StatesNo longer taking part
- Parkland Health Center - FarmingtonFarmington, United StatesTaking people
- Saint Francis HospitalFederal Way, United StatesNo longer taking part
- Lake Region Healthcare Corporation-Cancer CareFergus Falls, United StatesNo longer taking part
- Armes Family Cancer CenterFindlay, United StatesNo longer taking part
- Blanchard Valley HospitalFindlay, United StatesNo longer taking part
- Orion Cancer CareFindlay, United StatesNo longer taking part
- Cancer Hematology Centers - FlintFlint, United StatesTaking people
- Genesys Hurley Cancer InstituteFlint, United StatesTaking people
- Hurley Medical CenterFlint, United StatesTaking people
- Genesee Hematology Oncology PCFlint, United StatesNo longer taking part
- McFarland Clinic - Trinity Cancer CenterFort Dodge, United StatesTaking people
- Holy Cross HospitalFort Lauderdale, United StatesTaking people
- Mercy Hospital Fort SmithFort Smith, United StatesNo longer taking part
- UT Southwestern/Simmons Cancer Center-Fort WorthFort Worth, United StatesTaking people
- Essentia Health - FosstonFosston, United StatesNo longer taking part
- Atrium Medical Center-Middletown Regional HospitalFranklin, United StatesNo longer taking part
- Dayton Physicians LLC-AtriumFranklin, United StatesNo longer taking part
- Vanderbilt-Ingram Cancer Center Cool SpringsFranklin, United StatesNo longer taking part
- FMH James M Stockman Cancer InstituteFrederick, United StatesTaking people
- Unity HospitalFridley, United StatesNo longer taking part
- Saint Luke's Cancer Institute - FruitlandFruitland, United StatesNo longer taking part
- Central Ohio Breast and Endocrine SurgeryGahanna, United StatesNo longer taking part
- Illinois CancerCare-GalesburgGalesburg, United StatesNo longer taking part
- Western Illinois Cancer Treatment CenterGalesburg, United StatesNo longer taking part
- Central Care Cancer Center - Garden CityGarden City, United StatesNo longer taking part
- Aurora Health Care Germantown Health CenterGermantown, United StatesTaking people
- Aurora Cancer Care-GraftonGrafton, United StatesTaking people
- Nebraska Cancer Specialists/Oncology Hematology West PCGrand Island, United StatesNo longer taking part
- Central Care Cancer Center - Great BendGreat Bend, United StatesNo longer taking part
- Benefis Sletten Cancer InstituteGreat Falls, United StatesTaking people
- Great Falls ClinicGreat Falls, United StatesNo longer taking part
- Aurora BayCare Medical CenterGreen Bay, United StatesTaking people
- Marin Cancer Care IncGreenbrae, United StatesNo longer taking part
- UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, United StatesTaking people
- Dayton Physicians LLC-WayneGreenville, United StatesNo longer taking part
- Wayne HospitalGreenville, United StatesNo longer taking part
- Henry Ford Saint John Hospital - AcademicGrosse Pointe Woods, United StatesTaking people
- Henry Ford Saint John Hospital - Van ElslanderGrosse Pointe Woods, United StatesTaking people
- Henry Ford Saint John Hospital - BreastGrosse Pointe Woods, United StatesNo longer taking part
- Mount Carmel Grove City HospitalGrove City, United StatesNo longer taking part
- Memorial Sloan Kettering WestchesterHarrison, United StatesTaking people
- HaysMedHays, United StatesTaking people
- Lehigh Valley Hospital-HazletonHazleton, United StatesTaking people
- Saint Peter's Community HospitalHelena, United StatesNo longer taking part
- Cancer and Blood Specialists-HendersonHenderson, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada - HendersonHenderson, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada-Horizon RidgeHenderson, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada-Southeast HendersonHenderson, United StatesNo longer taking part
- Las Vegas Cancer Center-HendersonHenderson, United StatesNo longer taking part
- Las Vegas Urology - Green ValleyHenderson, United StatesNo longer taking part
- Las Vegas Urology - PebbleHenderson, United StatesNo longer taking part
- Oncology Las Vegas - HendersonHenderson, United StatesNo longer taking part
- Urology Specialists of Nevada - Green ValleyHenderson, United StatesNo longer taking part
- Margaret R Pardee Memorial HospitalHendersonville, United StatesTaking people
- Essentia Health Hibbing ClinicHibbing, United StatesTaking people
- Loyola Medicine Homer GlenHomer Glen, United StatesNo longer taking part
- CHI Saint Vincent Cancer Center Hot SpringsHot Springs, United StatesNo longer taking part
- Cancer Center of Kansas-IndependenceIndependence, United StatesNo longer taking part
- University of Iowa/Holden Comprehensive Cancer CenterIowa City, United StatesTaking people
- Swedish Cancer Institute-IssaquahIssaquah, United StatesNo longer taking part
- Allegiance HealthJackson, United StatesTaking people
- University of Mississippi Medical CenterJackson, United StatesTaking people
- Essentia Health - Jamestown ClinicJamestown, United StatesNo longer taking part
- McFarland Clinic - JeffersonJefferson, United StatesNo longer taking part
- MU Health Care Goldschmidt Cancer CenterJefferson City, United StatesNo longer taking part
- Jefferson HospitalJefferson Hills, United StatesNo longer taking part
- Emory Johns Creek HospitalJohns Creek, United StatesNo longer taking part
- Freeman Health SystemJoplin, United StatesNo longer taking part
- Mercy Hospital JoplinJoplin, United StatesNo longer taking part
- Logan Health Medical CenterKalispell, United StatesTaking people
- University Health Truman Medical CenterKansas City, United StatesTaking people
- CHI Health Good SamaritanKearney, United StatesNo longer taking part
- Ochsner Medical Center KennerKenner, United StatesNo longer taking part
- Kadlec Clinic Hematology and OncologyKennewick, United StatesTaking people
- Aurora Cancer Care-Kenosha SouthKenosha, United StatesTaking people
- Kettering Medical CenterKettering, United StatesTaking people
- First Dayton Cancer CareKettering, United StatesNo longer taking part
- Greater Dayton Cancer CenterKettering, United StatesNo longer taking part
- Illinois CancerCare-Kewanee ClinicKewanee, United StatesNo longer taking part
- Cancer Center of Kansas-KingmanKingman, United StatesNo longer taking part
- Kingman Regional Medical CenterKingman, United StatesNo longer taking part
- University of Tennessee - KnoxvilleKnoxville, United StatesNo longer taking part
- Providence Regional Cancer System-LaceyLacey, United StatesNo longer taking part
- Northwestern Medicine Lake Forest HospitalLake Forest, United StatesNo longer taking part
- Northwell Health/Center for Advanced MedicineLake Success, United StatesNo longer taking part
- CommonSpirit Saint Anthony Hospital Cancer CenterLakewood, United StatesNo longer taking part
- Saint Clare HospitalLakewood, United StatesNo longer taking part
- Fairfield Medical CenterLancaster, United StatesTaking people
- University of Michigan Health - Sparrow LansingLansing, United StatesTaking people
- Alliance for Childhood Diseases/Cure 4 the Kids FoundationLas Vegas, United StatesNo longer taking part
- Ann M Wierman MD LTDLas Vegas, United StatesNo longer taking part
- Cancer and Blood Specialists-ShadowLas Vegas, United StatesNo longer taking part
- Cancer and Blood Specialists-TenayaLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of NevadaLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada - Central ValleyLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada - NorthwestLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada - Town CenterLas Vegas, United StatesNo longer taking part
- Comprehensive Cancer Centers of Nevada-SummerlinLas Vegas, United StatesNo longer taking part
- Desert West SurgeryLas Vegas, United StatesNo longer taking part
- HealthCare Partners Medical Group Oncology/Hematology-Centennial HillsLas Vegas, United StatesNo longer taking part
- HealthCare Partners Medical Group Oncology/Hematology-Maryland ParkwayLas Vegas, United StatesNo longer taking part
- HealthCare Partners Medical Group Oncology/Hematology-San MartinLas Vegas, United StatesNo longer taking part
- HealthCare Partners Medical Group Oncology/Hematology-TenayaLas Vegas, United StatesNo longer taking part
- Hope Cancer Care of NevadaLas Vegas, United StatesNo longer taking part
- Las Vegas Cancer Center-Medical CenterLas Vegas, United StatesNo longer taking part
- Las Vegas Prostate Cancer CenterLas Vegas, United StatesNo longer taking part
- Las Vegas Urology - Cathedral RockLas Vegas, United StatesNo longer taking part
- Las Vegas Urology - PecosLas Vegas, United StatesNo longer taking part
- Las Vegas Urology - Smoke RanchLas Vegas, United StatesNo longer taking part
- Las Vegas Urology - SunsetLas Vegas, United StatesNo longer taking part
- Oncology Las Vegas - TenayaLas Vegas, United StatesNo longer taking part
- OptumCare Cancer Care at CharlestonLas Vegas, United StatesNo longer taking part
- OptumCare Cancer Care at Fort ApacheLas Vegas, United StatesNo longer taking part
- OptumCare Cancer Care at MountainViewLas Vegas, United StatesNo longer taking part
- Radiation Oncology Centers of Nevada CentralLas Vegas, United StatesNo longer taking part
- Radiation Oncology Centers of Nevada SoutheastLas Vegas, United StatesNo longer taking part
- Summerlin Hospital Medical CenterLas Vegas, United StatesNo longer taking part
- Sunrise Hospital and Medical CenterLas Vegas, United StatesNo longer taking part
- University Cancer CenterLas Vegas, United StatesNo longer taking part
- University Medical Center of Southern NevadaLas Vegas, United StatesNo longer taking part
- Urology Specialists of Nevada - CentralLas Vegas, United StatesNo longer taking part
- Urology Specialists of Nevada - NorthwestLas Vegas, United StatesNo longer taking part
- Urology Specialists of Nevada - SouthwestLas Vegas, United StatesNo longer taking part
- Lawrence Memorial HospitalLawrence, United StatesTaking people
- Cancer Centers of Southwest Oklahoma ResearchLawton, United StatesTaking people
- University of Kansas Cancer Center - Lee's SummitLee's Summit, United StatesTaking people
- CommonSpirit Saint Joseph Medical Center - East LexingtonLexington, United StatesNo longer taking part
- Saint Joseph Radiation Oncology Resource CenterLexington, United StatesNo longer taking part
- University of Kentucky/Markey Cancer CenterLexington, United StatesNo longer taking part
- Cancer Center of Kansas-LiberalLiberal, United StatesNo longer taking part
- Saint Rita's Medical CenterLima, United StatesNo longer taking part
- Saint Elizabeth Regional Medical CenterLincoln, United StatesNo longer taking part
- AdventHealth LittletonLittleton, United StatesNo longer taking part
- Trinity Health Saint Mary Mercy Livonia HospitalLivonia, United StatesTaking people
- Hope Cancer ClinicLivonia, United StatesNo longer taking part
- CommonSpirit Saint Joseph Hospital LondonLondon, United StatesNo longer taking part
- Longmont United HospitalLongmont, United StatesNo longer taking part
- Rocky Mountain Cancer Centers-LongmontLongmont, United StatesNo longer taking part
- PeaceHealth Saint John Medical CenterLongview, United StatesNo longer taking part
- Keck Medicine of USC KoreatownLos Angeles, United StatesTaking people
- Los Angeles General Medical CenterLos Angeles, United StatesTaking people
- USC / Norris Comprehensive Cancer CenterLos Angeles, United StatesTaking people
- UCLA / Jonsson Comprehensive Cancer CenterLos Angeles, United StatesNo longer taking part
- Jewish HospitalLouisville, United StatesNo longer taking part
- Saints Mary and Elizabeth HospitalLouisville, United StatesNo longer taking part
- UofL Health Medical Center NortheastLouisville, United StatesNo longer taking part
- Henry Ford Saint John Hospital - Macomb MedicalMacomb, United StatesTaking people
- Henry Ford Warren Hospital - Breast MacombMacomb, United StatesNo longer taking part
- Illinois CancerCare-MacombMacomb, United StatesNo longer taking part
- Cancer Center of Kansas-ManhattanManhattan, United StatesNo longer taking part
- OhioHealth Mansfield HospitalMansfield, United StatesTaking people
- Fairview Clinics and Surgery Center Maple GroveMaple Grove, United StatesNo longer taking part
- Minnesota Oncology Hematology PA-MaplewoodMaplewood, United StatesNo longer taking part
- Saint John's Hospital - HealtheastMaplewood, United StatesNo longer taking part
- Marietta Memorial HospitalMarietta, United StatesTaking people
- Aurora Bay Area Medical Group-MarinetteMarinette, United StatesTaking people
- OhioHealth Marion General HospitalMarion, United StatesTaking people
- Saint Mary's Oncology/Hematology Associates of MarletteMarlette, United StatesNo longer taking part
- McFarland Clinic - MarshalltownMarshalltown, United StatesTaking people
- Marshfield Medical Center-MarshfieldMarshfield, United StatesTaking people
- Contra Costa Regional Medical CenterMartinez, United StatesNo longer taking part
- Memorial HospitalMarysville, United StatesTaking people
- Carle Physician Group-Mattoon/CharlestonMattoon, United StatesTaking people
- Loyola University Medical CenterMaywood, United StatesTaking people
- Cancer Center of Kansas - McPhersonMcPherson, United StatesNo longer taking part
- Marjorie Weinberg Cancer Center at Loyola-GottliebMelrose Park, United StatesNo longer taking part
- Idaho Urologic Institute-MeridianMeridian, United StatesNo longer taking part
- Saint Luke's Cancer Institute - MeridianMeridian, United StatesNo longer taking part
- Mary Bird Perkins Cancer Center - MetairieMetairie, United StatesTaking people
- East Jefferson General HospitalMetairie, United StatesNo longer taking part
- LSU Healthcare Network / Metairie Multi-Specialty ClinicMetairie, United StatesNo longer taking part
- Mount Sinai Medical CenterMiami Beach, United StatesNo longer taking part
- Memorial Sloan Kettering MonmouthMiddletown, United StatesTaking people
- Aurora Cancer Care-MilwaukeeMilwaukee, United StatesTaking people
- Aurora Saint Luke's Medical CenterMilwaukee, United StatesTaking people
- Aurora Sinai Medical CenterMilwaukee, United StatesTaking people
- NYU Langone Hospital - Long IslandMineola, United StatesNo longer taking part
- Hennepin County Medical CenterMinneapolis, United StatesTaking people
- Abbott-Northwestern HospitalMinneapolis, United StatesNo longer taking part
- Health Partners IncMinneapolis, United StatesNo longer taking part
- Marshfield Medical Center - MinocquaMinocqua, United StatesTaking people
- Community Medical CenterMissoula, United StatesTaking people
- Saint Patrick Hospital - Community HospitalMissoula, United StatesNo longer taking part
- UPMC Hillman Cancer Center - MonroevilleMonroeville, United StatesTaking people
- Forbes HospitalMonroeville, United StatesNo longer taking part
- UPMC Cancer Center - MonroevilleMonroeville, United StatesNo longer taking part
- Monticello Cancer CenterMonticello, United StatesNo longer taking part
- Memorial Sloan Kettering BergenMontvale, United StatesTaking people
- Knox Community HospitalMount Vernon, United StatesTaking people
- SSM Health Good SamaritanMount Vernon, United StatesNo longer taking part
- ProHealth D N Greenwald CenterMukwonago, United StatesTaking people
- Arnold Palmer Cancer Center Medical Oncology NorwinN. Huntingdon, United StatesTaking people
- Saint Alphonsus Cancer Care Center-NampaNampa, United StatesTaking people
- Saint Luke's Cancer Institute - NampaNampa, United StatesNo longer taking part
- Vanderbilt University/Ingram Cancer CenterNashville, United StatesTaking people
- Vanderbilt Breast Center at One Hundred OaksNashville, United StatesNo longer taking part
- Allegheny Valley HospitalNatrona Heights, United StatesNo longer taking part
- UC Comprehensive Cancer Center at Silver CrossNew Lenox, United StatesTaking people
- Louisiana State University Health Science CenterNew Orleans, United StatesNo longer taking part
- Ochsner Medical Center JeffersonNew Orleans, United StatesNo longer taking part
- Tulane University School of MedicineNew Orleans, United StatesNo longer taking part
- Cancer Center of Western WisconsinNew Richmond, United StatesNo longer taking part
- New Ulm Medical CenterNew Ulm, United StatesNo longer taking part
- Memorial Sloan-Kettering Cancer CenterNew York, United StatesTaking people
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer CenterNew York, United StatesTaking people
- NYP/Weill Cornell Medical CenterNew York, United StatesTaking people
- Laura and Isaac Perlmutter Cancer Center at NYU LangoneNew York, United StatesNo longer taking part
- Licking Memorial HospitalNewark, United StatesTaking people
- Newark Radiation OncologyNewark, United StatesNo longer taking part
- Providence Newberg Medical CenterNewberg, United StatesTaking people
- USC Norris Oncology/Hematology-Newport BeachNewport Beach, United StatesTaking people
- Cancer Center of Kansas - NewtonNewton, United StatesNo longer taking part
- Henry Ford Medical Center-ColumbusNovi, United StatesTaking people
- Cancer Care Center of O'FallonO'Fallon, United StatesNo longer taking part
- Rush MD Anderson Cancer Center at Rush Oak ParkOak Park, United StatesNo longer taking part
- Alta Bates Summit Medical Center - Summit CampusOakland, United StatesNo longer taking part
- Bay Area Tumor InstituteOakland, United StatesNo longer taking part
- ProHealth Oconomowoc Memorial HospitalOconomowoc, United StatesTaking people
- University of Oklahoma Health Sciences CenterOklahoma City, United StatesTaking people
- Mercy Hospital Oklahoma CityOklahoma City, United StatesNo longer taking part
- The University of Kansas Cancer Center - OlatheOlathe, United StatesTaking people
- Nebraska Medicine-Village PointeOmaha, United StatesTaking people
- University of Nebraska Medical CenterOmaha, United StatesTaking people
- Alegent Health Bergan Mercy Medical CenterOmaha, United StatesNo longer taking part
- Alegent Health Immanuel Medical CenterOmaha, United StatesNo longer taking part
- Alegent Health Lakeside HospitalOmaha, United StatesNo longer taking part
- Nebraska Cancer Specialists/Oncology Hematology West PC - MECCOmaha, United StatesNo longer taking part
- Nebraska Methodist HospitalOmaha, United StatesNo longer taking part
- Oncology Associates PCOmaha, United StatesNo longer taking part
- Saint Alphonsus Cancer Care Center-OntarioOntario, United StatesTaking people
- Providence Willamette Falls Medical CenterOregon City, United StatesTaking people
- University of Chicago Medicine-Orland ParkOrland Park, United StatesTaking people
- Orlando Health Cancer InstituteOrlando, United StatesTaking people
- Vince Lombardi Cancer Clinic - OshkoshOshkosh, United StatesTaking people
- Illinois CancerCare-Ottawa ClinicOttawa, United StatesNo longer taking part
- Hope Cancer Care of Nevada-PahrumpPahrump, United StatesNo longer taking part
- Midlands Community HospitalPapillion, United StatesNo longer taking part
- Essentia Health - Park RapidsPark Rapids, United StatesNo longer taking part
- AdventHealth ParkerParker, United StatesNo longer taking part
- Cancer Center of Kansas - ParsonsParsons, United StatesNo longer taking part
- Lahey Clinic PeabodyPeabody, United StatesTaking people
- Illinois CancerCare-PekinPekin, United StatesNo longer taking part
- Illinois CancerCare-PeoriaPeoria, United StatesNo longer taking part
- Methodist Medical Center of IllinoisPeoria, United StatesNo longer taking part
- Mercy Health - Perrysburg HospitalPerrysburg, United StatesNo longer taking part
- Illinois CancerCare-PeruPeru, United StatesNo longer taking part
- Valley Radiation OncologyPeru, United StatesNo longer taking part
- Mayo Clinic Hospital in ArizonaPhoenix, United StatesTaking people
- Cancer Center at Saint Joseph'sPhoenix, United StatesNo longer taking part
- Freeman Physician Group of PittsburgPittsburg, United StatesTaking people
- Mercy Hospital PittsburgPittsburg, United StatesNo longer taking part
- UPMC Hillman Cancer CenterPittsburgh, United StatesTaking people
- UPMC-Passavant HospitalPittsburgh, United StatesTaking people
- UPMC-Saint Clair Hospital Cancer CenterPittsburgh, United StatesTaking people
- Allegheny General HospitalPittsburgh, United StatesNo longer taking part
- UPMC-Shadyside HospitalPittsburgh, United StatesNo longer taking part
- West Penn HospitalPittsburgh, United StatesNo longer taking part
- Michigan Healthcare Professionals PontiacPontiac, United StatesTaking people
- Trinity Health IHA Medical Group-Alice Gustafson CenterPontiac, United StatesTaking people
- Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, United StatesTaking people
- Hope Cancer CenterPontiac, United StatesNo longer taking part
- Huron Medical Center PCPort Huron, United StatesNo longer taking part
- Lake Huron Medical CenterPort Huron, United StatesNo longer taking part
- Oregon Health and Science UniversityPortland, United StatesTaking people
- Providence Portland Medical CenterPortland, United StatesTaking people
- Providence Saint Vincent Medical CenterPortland, United StatesTaking people
- Southern Ohio Medical CenterPortsmouth, United StatesTaking people
- Kootenai Clinic Cancer Services - Post FallsPost Falls, United StatesTaking people
- Harrison HealthPartners Hematology and Oncology-PoulsboPoulsbo, United StatesNo longer taking part
- Cancer Center of Kansas - PrattPratt, United StatesNo longer taking part
- Fairview Northland Medical CenterPrinceton, United StatesNo longer taking part
- Illinois CancerCare-PrincetonPrinceton, United StatesNo longer taking part
- Saint Mary Corwin Medical CenterPueblo, United StatesNo longer taking part
- Aurora Cancer Care-RacineRacine, United StatesTaking people
- Saint Charles Health System-RedmondRedmond, United StatesNo longer taking part
- Radiation Oncology AssociatesReno, United StatesNo longer taking part
- Renown Regional Medical CenterReno, United StatesNo longer taking part
- Saint Mary's Regional Medical CenterReno, United StatesNo longer taking part
- Valley Medical CenterRenton, United StatesTaking people
- Marshfield Medical Center-Rice LakeRice Lake, United StatesTaking people
- UT Southwestern Clinical Center at Richardson/PlanoRichardson, United StatesTaking people
- Reid HealthRichmond, United StatesNo longer taking part
- North Memorial Medical Health CenterRobbinsdale, United StatesNo longer taking part
- Mayo Clinic in RochesterRochester, United StatesTaking people
- University of RochesterRochester, United StatesNo longer taking part
- Henry Ford Rochester HospitalRochester Hills, United StatesNo longer taking part
- Mercy Clinic-Rolla-Cancer and HematologyRolla, United StatesNo longer taking part
- Phelps Health Delbert Day Cancer InstituteRolla, United StatesNo longer taking part
- MyMichigan Medical Center SaginawSaginaw, United StatesTaking people
- Oncology Hematology Associates of Saginaw Valley PCSaginaw, United StatesNo longer taking part
- Heartland Regional Medical CenterSaint Joseph, United StatesNo longer taking part
- Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, United StatesNo longer taking part
- Regions HospitalSaint Paul, United StatesTaking people
- United HospitalSaint Paul, United StatesNo longer taking part
- Sainte Genevieve County Memorial HospitalSainte Genevieve, United StatesTaking people
- Salina Regional Health CenterSalina, United StatesTaking people
- Cancer Center of Kansas - SalinaSalina, United StatesNo longer taking part
- Pacific Central Coast Health Center-San Luis ObispoSan Luis Obispo, United StatesNo longer taking part
- Kootenai Clinic Cancer Services - SandpointSandpoint, United StatesTaking people
- Essentia Health SandstoneSandstone, United StatesTaking people
- Mission Hope Medical Oncology - Santa MariaSanta Maria, United StatesNo longer taking part
- Mayo Clinic in ArizonaScottsdale, United StatesTaking people
- Pacific Gynecology SpecialistsSeattle, United StatesNo longer taking part
- Swedish Medical Center-Ballard CampusSeattle, United StatesNo longer taking part
- Swedish Medical Center-Cherry HillSeattle, United StatesNo longer taking part
- Swedish Medical Center-First HillSeattle, United StatesNo longer taking part
- PeaceHealth United General Medical CenterSedro-Woolley, United StatesNo longer taking part
- Saint Francis Regional Medical CenterShakopee, United StatesNo longer taking part
- Vince Lombardi Cancer Clinic-SheboyganSheboygan, United StatesTaking people
- Henry Ford Macomb Health Center - Shelby TownshipShelby, United StatesNo longer taking part
- Providence Regional Cancer System-SheltonShelton, United StatesNo longer taking part
- Jewish Hospital Medical Center SouthShepherdsville, United StatesNo longer taking part
- Welch Cancer CenterSheridan, United StatesNo longer taking part
- Memorial Hospital EastShiloh, United StatesTaking people
- Saint Joseph Medical Center Hematology and Oncology - SilverdaleSilverdale, United StatesNo longer taking part
- Southern Illinois University School of MedicineSpringfield, United StatesTaking people
- Springfield ClinicSpringfield, United StatesTaking people
- Springfield Memorial HospitalSpringfield, United StatesTaking people
- Springfield Regional Cancer CenterSpringfield, United StatesTaking people
- CoxHealth South HospitalSpringfield, United StatesNo longer taking part
- Mercy Hospital SpringfieldSpringfield, United StatesNo longer taking part
- Mercy Medical CenterSpringfield, United StatesNo longer taking part
- Springfield Regional Medical CenterSpringfield, United StatesNo longer taking part
- Mercy Hospital Saint LouisSt Louis, United StatesTaking people
- Mercy Hospital SouthSt Louis, United StatesTaking people
- Missouri Baptist Medical CenterSt Louis, United StatesTaking people
- Siteman Cancer Center at Christian HospitalSt Louis, United StatesTaking people
- Siteman Cancer Center-South CountySt Louis, United StatesTaking people
- Washington University School of MedicineSt Louis, United StatesTaking people
- Mercy Infusion Center - ChippewaSt Louis, United StatesNo longer taking part
- Bhadresh Nayak MD PC-Sterling HeightsSterling Heights, United StatesNo longer taking part
- Marshfield Medical Center-River Region at Stevens PointStevens Point, United StatesTaking people
- Lakeview HospitalStillwater, United StatesTaking people
- Missouri Baptist Sullivan HospitalSullivan, United StatesTaking people
- Aurora Medical Center in SummitSummit, United StatesTaking people
- Southwest Illinois Health Services LLPSwansea, United StatesNo longer taking part
- State University of New York Upstate Medical UniversitySyracuse, United StatesNo longer taking part
- Franciscan Research Center-Northwest Medical PlazaTacoma, United StatesNo longer taking part
- Northwest Medical Specialties PLLCTacoma, United StatesNo longer taking part
- MyMichigan Medical Center TawasTawas City, United StatesTaking people
- Mercy Health - Saint Anne HospitalToledo, United StatesNo longer taking part
- Mercy Health - Saint Vincent HospitalToledo, United StatesNo longer taking part
- University of Kansas Health System Saint Francis CampusTopeka, United StatesTaking people
- Dayton Physicians LLC - TroyTroy, United StatesNo longer taking part
- Upper Valley Medical CenterTroy, United StatesNo longer taking part
- Banner University Medical Center - TucsonTucson, United StatesNo longer taking part
- University of Arizona Cancer Center-North CampusTucson, United StatesNo longer taking part
- University of Arizona Cancer Center-Orange Grove CampusTucson, United StatesNo longer taking part
- Oklahoma Cancer Specialists and Research Institute-TulsaTulsa, United StatesNo longer taking part
- Saint Luke's Cancer Institute - Twin FallsTwin Falls, United StatesNo longer taking part
- Vince Lombardi Cancer Clinic-Two RiversTwo Rivers, United StatesTaking people
- Memorial Sloan Kettering NassauUniondale, United StatesTaking people
- Carle Cancer CenterUrbana, United StatesTaking people
- The Carle Foundation HospitalUrbana, United StatesNo longer taking part
- PeaceHealth Southwest Medical CenterVancouver, United StatesNo longer taking part
- Essentia Health Virginia ClinicVirginia, United StatesTaking people
- Ridgeview Medical CenterWaconia, United StatesTaking people
- Providence Saint Mary Regional Cancer CenterWalla Walla, United StatesNo longer taking part
- Epic Care Cyberknife CenterWalnut Creek, United StatesNo longer taking part
- Henry Ford Health Warren HospitalWarren, United StatesTaking people
- Henry Ford Warren Hospital - GLCMSWarren, United StatesTaking people
- Advanced Breast Care Center PLLCWarren, United StatesNo longer taking part
- Henry Ford Madison Heights Hospital - BreastWarren, United StatesNo longer taking part
- Macomb Hematology Oncology PCWarren, United StatesNo longer taking part
- Saint Joseph Warren HospitalWarren, United StatesNo longer taking part
- Illinois CancerCare - WashingtonWashington, United StatesNo longer taking part
- Mercy Hospital WashingtonWashington, United StatesNo longer taking part
- MedStar Georgetown University HospitalWashington D.C., United StatesTaking people
- UI Health Care Mission Cancer and Blood - Waukee ClinicWaukee, United StatesTaking people
- ProHealth Waukesha Memorial HospitalWaukesha, United StatesTaking people
- UW Cancer Center at ProHealth CareWaukesha, United StatesTaking people
- Aurora Cancer Care-Milwaukee WestWauwatosa, United StatesTaking people
- Cancer Center of Kansas - WellingtonWellington, United StatesNo longer taking part
- Aurora West Allis Medical CenterWest Allis, United StatesTaking people
- Henry Ford West Bloomfield HospitalWest Bloomfield, United StatesTaking people
- Saint Mary's Oncology/Hematology Associates of West BranchWest Branch, United StatesNo longer taking part
- University of Cincinnati Cancer Center-West ChesterWest Chester, United StatesNo longer taking part
- Mercy Medical Center-West LakesWest Des Moines, United StatesNo longer taking part
- OhioHealth Westerville Medical Campus/Westerville Cancer CenterWesterville, United StatesTaking people
- Saint Ann's HospitalWesterville, United StatesTaking people
- Marshfield Medical Center - WestonWeston, United StatesTaking people
- University of Kansas Hospital-Westwood Cancer CenterWestwood, United StatesTaking people
- Wexford Health and Wellness PavilionWexford, United StatesNo longer taking part
- Ascension Via Christi Hospitals WichitaWichita, United StatesNo longer taking part
- Cancer Center of Kansas - WichitaWichita, United StatesNo longer taking part
- Cancer Center of Kansas-Wichita Medical Arts TowerWichita, United StatesNo longer taking part
- Rice Memorial HospitalWillmar, United StatesNo longer taking part
- Beth Israel Deaconess Medical Center/Winchester Center for Cancer CareWinchester, United StatesNo longer taking part
- Cancer Center of Kansas - WinfieldWinfield, United StatesNo longer taking part
- Minnesota Oncology Hematology PA-WoodburyWoodbury, United StatesNo longer taking part
- Henry Ford Wyandotte HospitalWyandotte, United StatesTaking people
- Fairview Lakes Medical CenterWyoming, United StatesNo longer taking part
- North Star Lodge Cancer Center at Yakima Valley Memorial HospitalYakima, United StatesNo longer taking part
- Providence Regional Cancer System-YelmYelm, United StatesNo longer taking part
- Rush-Copley Healthcare CenterYorkville, United StatesNo longer taking part
- Saint Elizabeth Youngstown HospitalYoungstown, United StatesNo longer taking part
- Huron Gastroenterology PCYpsilanti, United StatesTaking people
- Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti, United StatesTaking people
- Genesis Healthcare System Cancer Care CenterZanesville, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Cancer Institute (NCI)
- Trial code
- NCT03866382
- Record updated
- 4 November 2026
- Original description
This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.Read full original descriptionShow less
A Phase II Study of Ipilimumab, Cabozantinib, and Nivolumab in Rare Genitourinary Cancers (ICONIC)
This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.
Inclusion: Metastatic disease defined as new or progressive lesions on cross-sectional imaging or bone scan. Patients must have at least:; One measurable site of disease as per Response Evaluation Criteria in Solid Tumors (RECIST) version (v) 1.1; One bone lesion on bone scan (tec99 or sodium fluoride [NaF] PET/CT, CT or MRI) for the bone-only cohort; Histologically confirmed diagnosis of one of the following metastatic cohorts:; Small cell/ neuroendocrine carcinoma of the bladder (Cohort A)- All urothelial carcinomas with any amount of neuroendocrine differentiation (including small cell differentiation) will be included. If the tumor is purely neuroendocrine, metastasis from another site of origin should be clinically excluded; Adenocarcinoma of the bladder, or urachal adenocarcinoma, or bladder/urethra clear cell adenocarcinoma (Cohort B) - must be pure (per World Health Organization [WHO] definition), (i.e. urothelial carcinoma with glandular differentiation is not considered a pure adenocarcinoma; Squamous cell carcinoma of the bladder (Cohort C) - must be pure (i.e. urothelial carcinoma with squamous differentiation is not considered a pure squamous cell carcinoma); Plasmacytoid urothelial carcinoma (Cohort D) - Tumor should show predominantly > or equal ~ 50% plasmacytoid histology (including all types of discohesive growth, such as tumors with signet-ring and/or rhabdoid features as well); Any penile cancer (Cohort E); Sarcomatoid renal cell carcinoma (Cohort F) - Tumor should be predominantly sarcomatoid ~ 50% (including rhabdoid differentiation) is also unclassified renal cell carcinomas (RCCs): all (assuming they are high grade with metastasis) malignant angiomyolipomas are allowed; Other miscellaneous histologic variants of the urothelial carcinoma, such as, but not limited to (Cohort G) : Micropapillary (Tumor should show predominantly > or equal 50% micropapillary architecture), giant cell, lipid-rich, clear cell and nested variants (Tumor should predominantly > or equal 50% show these features), large cell neuroendocrine carcinoma, lymphoepithelioma-like carcinoma and mixed patterns will be considered, as well as small cell neuroendocrine prostate cancer (Only treatment-naïve primary small cell of prostate with any amount of small cell component allowed. Post-treatment small cell prostatic carcinomas are not allowed), Malignant testicular Sertoli or Leydig cell tumors, and papillary and chromophobe RCC; Note: Translocation positive renal cell carcinoma patients are eligible. However, AREN1721 should be considered before this trial; Sarcomatoid urothelial carcinoma (Cohort H) - Tumor should show predominantly ~ 50% sarcomatoid differentiation; Renal medullary carcinoma (Cohort I) - Per World Health Organization (WHO) definition, ideally confirmed with immunostains; Bone-only metastatic GU tumors (non-prostate) (Cohort J) - All genitourinary histologies, except prostate are eligible; Renal Collecting Duct Carcinoma (Cohort K) - Per WHO definition (medullary involvement, predominant tubular morphology, desmoplastic stromal reaction, high grade cytology, infiltrative growth pattern, and absence of other renal cell carcinoma subtype or urothelial carcinoma); Urethra carcinoma (Cohort L) - May be of any histology but if urothelial carcinoma then must be isolated to the urethra and not have metachronous or synchronous urothelial carcinoma of the bladder; H\&E slides from diagnostic tumor tissue for retrospective central pathology review; Patients may have received up to 2 systemic anti-cancer treatments or be treatment naive. Patients with small cell carcinoma should have received a platinum-based combination regimen either as neoadjuvant, adjuvant or first-line treatment). Patients in the bone-only cohort may be urothelial carcinoma histology but must receive standard cisplatin-based chemotherapy (if cisplatin-eligible); Age >= 18 years; Patients must be able to swallow oral formulation of the tablets; Karnofsky performance status >= 80%; Absolute neutrophil count (ANC) >= 1,000/mcL; Platelet count >= 75,000/mcL; Total bilirubin =< 1.5 x upper limit of normal (ULN). For subjects with known Gilbert's disease or similar syndrome with slow conjugation of bilirubin, total bilirubin =< 3.0 mg/dL; Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 3.0 x institutional upper limit of normal (ULN) (or =< 5 x ULN for patients with liver metastases or Gilbert's disease); Creatinine =< 1.5 x upper limit of normal (ULN) OR creatinine clearance >= 40 mL/min/1.73 m\^2 (calculated using the Chronic Kidney Disease Epidemiology [CKD-EPI] equation or Cockcroft-Gault formula) for patients with creatinine levels above institutional normal; Hemoglobin >= 9 g/dL (transfusion of packed red blood cells [PRBCs] allowed); Serum albumin >= 3.2 g/dL; Lipase and amylase =< 2.0 x ULN and no radiologic (on baseline anatomical imaging) or clinical evidence of pancreatitis; Prior treatment with MET or VEGFR inhibitors is allowed. However, prior cabozantinib will not be allowed. Also, patients that have received both prior MET or VEGF and prior PD-1/PD-L1/CTLA-4 (sequentially or in combination) are also not allowed; No prior treatment with any therapy on the PD-1/PD-L1 axis or anti- CTLA-4/CTLA-4 inhibitors with the exception of patients with "urothelial carcinoma" histology (cohorts D, H, J, L); Human immunodeficiency virus (HIV)-positive patients are eligible if on stable dose of highly active antiretroviral therapy (HAART), no clinically significant drug-drug interactions are anticipated with the current HAART regimen, CD4 counts are greater than 350 and viral load is undetectable; Patients with rheumatoid arthritis and other rheumatologic arthropathies, Sjogren's syndrome and psoriasis controlled with topical medication only and patients with positive serology, such as antinuclear antibodies (ANA), anti-thyroid antibodies etc. are eligible but should be considered for rheumatologic evaluation for the presence of target organ involvement and potential need for systemic treatment; Patients with vitiligo, endocrine deficiencies including thyroiditis managed with replacement hormones or medications (e.g. thyroiditis managed with propylthiouracil [PTU] or methimazole) including physiologic oral corticosteroids are eligible; Patients who have evidence of active or acute diverticulitis, intra-abdominal abscess, and gastrointestinal (GI) obstruction, within 12 months are not eligible; Women of childbearing potential must have a negative pregnancy test =< 7 days prior to registration; Women of childbearing potential include women who have experienced menarche and who have not undergone successful surgical sterilization (hysterectomy, bilateral tubal ligation, or bilateral oophorectomy) or are not postmenopausal. Post menopause is defined as amenorrhea >= 12 consecutive months. Note: women who have been amenorrheic for 12 or more months are still considered to be of childbearing potential if the amenorrhea is possibly due to prior chemotherapy, antiestrogens, ovarian suppression or any other reversible reason; Pregnant women may not participate in this study because with cabozantinib, nivolumab, and ipilimumab have potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with cabozantinib, nivolumab, and ipilimumab, breastfeeding should be discontinued if the mother is treated with these agents; The patient has received no cytotoxic chemotherapy (including investigational cytotoxic chemotherapy) or biologic agents (e.g., cytokines or antibodies) within 2 weeks before the first dose of study treatment; The patient has received no radiation therapy:; To the lungs and mediastinum or abdomen within 4 weeks before the first dose of study treatment, or has ongoing complications, or is healing from prior radiation therapy; To brain metastasis within 3 weeks for whole-brain radiotherapy (WBXRT), and 2 weeks for stereotactic body radiation therapy (SBRT) before the first dose of study treatment; To the abdomen within 4 weeks before the first dose of study treatment, or has ongoing complications, or is healing from prior radiation therapy; To any other site(s) within 2 weeks before the first dose of study treatment; The patient has received no radionuclide treatment within 6 weeks of the first dose of study treatment; The patient has received no prior treatment with a small molecule kinase inhibitor within 14 days or five half-lives of the compound or active metabolites, whichever is longer, before the first dose of study treatment; The patient has received no prior treatment with hormonal therapy within 14 days or five half-lives of the compound or active metabolites, whichever is longer, before the first dose of study treatment. Subjects receiving gonadotropin-releasing hormone (GnRH) agonists and antagonists are allowed to participate; The patient has not received any other type of investigational agent within 14 days before the first dose of study treatment; The patient must have recovered to baseline or Common Terminology Criteria for Adverse Events (CTCAE) =< grade 1 from toxicity due to all prior therapies except alopecia, neuropathy and other non-clinically significant adverse events (AEs) defined as lab elevation with no associated symptoms or sequelae; The patient may not have active brain metastases or epidural disease. Patients with brain metastases previously treated with whole brain radiation or radiosurgery who are asymptomatic and do not require steroid treatment for at least 2 weeks before starting study treatment are eligible. Neurosurgical resection of brain metastases or brain biopsy is permitted if completed at least 3 months before starting study treatment. Baseline brain imaging with contrast-enhanced CT or MRI scans for subjects with known brain metastases is required to confirm eligibility; No concomitant treatment with warfarin. Aspirin (up to 325 mg/day), thrombin or factor Xa inhibitors, low-dose warfarin (=< 1 mg/day), prophylactic and therapeutic low molecular weight heparin (LMWH) are permitted; No chronic concomitant treatment with strong CYP3A4 inducers (e.g., dexamethasone, phenytoin, carbamazepine, rifampin, rifabutin, rifapentine, phenobarbital, and St. John's wort) or strong CYP3A4 inhibitors; Because the lists of these agents are constantly changing, it is important to regularly consult medical reference texts such as the Physicians' Desk Reference may also provide this information. As part of the enrollment/informed consent procedures, the patient will be counseled on the risk of interactions with other agents, and what to do if new medications need to be prescribed or if the patient is considering a new over-the-counter medicine or herbal product; The patient has not experienced any of the following:; Clinically-significant gastrointestinal bleeding within 6 months before the first dose of study treatment; Hemoptysis of >= 0.5 teaspoon (2.5 mL) of red blood per day within 1 months before the first dose of study treatment; Any other signs indicative of pulmonary hemorrhage within 3 months before the first dose of study treatment; The patient has no tumor invading any major blood vessels; The patient has no evidence of tumor invading the GI tract (esophagus, stomach, small or large bowel, rectum or anus), or any evidence of endotracheal or endobronchial tumor within 28 days before the first dose of cabozantinib. Patients with rectal tumor masses are not eligible; The patient has no uncontrolled, significant intercurrent or recent illness including, but not limited to, the following conditions:; Cardiovascular disorders including:; Congestive heart failure (CHF): New York Heart Association (NYHA) class III (moderate) or class IV (severe) at the time of screening; Concurrent uncontrolled hypertension defined as sustained blood pressure (BP) > 150 mm Hg systolic, or > 90 mm Hg diastolic despite optimal antihypertensive treatment within 7 days of the first dose of study treatment; The subject has a corrected QT interval calculated by the Fridericia formula (QTcF) > 500 ms within 28 days before randomization. Note: if initial QTcF is found to be > 500 ms, two additional electrocardiograms (EKGs) separated by at least 3 minutes should be performed. If the average of these three consecutive results for QTcF is =< 500 ms, the subject meets eligibility in this regard; Any history of congenital long QT syndrome; Any of the following within 6 months before registration of study treatment:; Unstable angina pectoris; Clinically-significant cardiac arrhythmias (patients with atrial fibrillation are eligible); Stroke (including transient ischemic attack [TIA], or other ischemic event); Myocardial infarction; Cardiomyopathy; No significant gastrointestinal disorders particularly those associated with a high risk of perforation or fistula formation including:; Any of the following that have not resolved within 28 days before the first dose of study treatment:; Active peptic ulcer disease; Acute diverticulitis, cholecystitis, symptomatic cholangitis or appendicitis, or malabsorption syndrome; None of the following within 2 years before the first dose of study treatment:; Abdominal fistula or genitourinary fistula; Gastrointestinal perforation; Bowel obstruction or gastric outlet obstruction; Intra-abdominal abscess. Note: Complete resolution of an intra-abdominal abscess must be confirmed prior to initiating treatment with cabozantinib even if the abscess occurred more than 2 years before the first dose of study treatment; Disorders associated with a high risk of fistula formation including percutaneous endoscopic gastrostomy (PEG) tube placement are not eligible; No other clinically significant disorders such as:; Severe active infection requiring IV systemic treatment within 14 days before the first dose of study treatment; Serious non-healing wound/ulcer/bone fracture within 28 days before the first dose of study treatment; History of organ or allogeneic stem cell transplant; Concurrent uncompensated hypothyroidism or thyroid dysfunction within 7 days before the first dose of study treatment (for asymptomatic patients with an elevated thyroid-stimulating hormone [TSH], thyroid replacement may be initiated if clinically indicated without delaying the start of study treatment); No history of major surgery as follows:; Major surgery within 3 months of the first dose of cabozantinib; however, if there were no wound healing complications, patients with rapidly growing aggressive cancers, may start as soon as 6 weeks if wound has completely healed post-surgery; Minor surgery within 1 month of the first dose of cabozantinib if there were no wound healing complications or within 3 months of the first dose of cabozantinib if there were wound complications excluding core biopsies and mediport placement; Complete wound healing from prior surgery must be confirmed before the first dose of cabozantinib irrespective of the time from surgery; No history of severe hypersensitivity reaction to any monoclonal antibody; No evidence of active malignancy, requiring systemic treatment within 2 years of registration; No history of allergic reactions attributed to compounds of similar chemical or biologic composition to cabozantinib, nivolumab, ipilimumab or other agents used in study; No positive test for hepatitis B virus surface antigen (HBV sAg) or hepatitis C virus ribonucleic acid (HCV antibody) indicating acute or chronic infection. If HBV sAG is positive, subsequent ribonucleic acid (RNA) polymerase chain reaction (PCR) must be negative; No patients with active autoimmune disease or history of autoimmune disease that might recur, which may affect vital organ function or require immune suppressive treatment including systemic corticosteroids. These include, but are not limited to patients with a history of immune related neurologic disease, multiple sclerosis, autoimmune (demyelinating) neuropathy, Guillain-Barre syndrome, myasthenia gravis; systemic autoimmune disease such as systemic lupus erythematosus (SLE), connective tissue diseases, scleroderma, inflammatory bowel disease (IBD), Crohn's, ulcerative colitis, hepatitis; and patients with a history of toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome, or phospholipid syndrome should be excluded because of the risk of recurrence or exacerbation of disease.