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Taking people in South KoreaNo phase

Studies kidney tissue from people with kidney inflammation diseases over time

Collects kidney biopsy samples and long-term data from people with glomerular kidney diseases.

Plain-language title generated from the registry record
Registry title: KOrea Renal Biobank NEtwoRk System TOward NExt-generation Analysis

Key facts

Where
Chuncheon, Daegu, and Seoul, South KoreaSee the 6 sites

Where in South Korea

  • Kangwon National University HospitalChuncheon, South KoreaTaking people
  • Keimyung University - Dongsan Medical CenterDaegu, South KoreaTaking people
  • Chung-Ang University HosptialSeoul, South KoreaTaking people
  • Seoul National University HospitalSeoul, South KoreaTaking people
  • Severance hospitalSeoul, South KoreaTaking people
  • SMG-SNU Boramae Medical CenterSeoul, South KoreaTaking people

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Trial details

Who runs it
Seoul National University Hospital
Trial code
NCT03929887
Record updated
12 February 2020
Original description
Glomerulonephritis (GN) generates an enormous individual and social economic burden. However, the therapeutic options are largely based on clinical and pathological parameters and the individual response to therapy or prognosis is uncertain.Read full original descriptionShow less

Multicenter Prospective Cohort of Kidney Biopsy for Glomerular Disease Research

Glomerulonephritis (GN) generates an enormous individual and social economic burden. However, the therapeutic options are largely based on clinical and pathological parameters and the individual response to therapy or prognosis is uncertain.

Recently, along with advances in molecular analysis and computational bioinformatics, genomic data from human renal biopsies could provide a strong foundation for the future of precision medicine in nephrology.

In response to a request for applications by the Ministry of Health and Welfare of Korea for the creation of Clinical Research Registry, multi-center N network has been established for prospective cohort with kidney biopsy samples (KORNERSTONE).

Through this Network the investigators hope to understand the fundamental biology of glomerulonephritis and aim to bank long-term observational data and corresponding biological data including genomic data from kidney tissues, and kidney pathologic data which is digitalized This database is archived to a web-based platform to access easily and further enrich for researchers.

Inclusion criteria; Patient suspected of glomerular disease who received kidney biopsy in participating university medical centers; Children (age<18 years) also included; Exclusion criteria - Patients who previously received a kidney transplant.

ClinicalTrials.gov NCT03929887