Tests a low protein diet to help protect kidneys in chronic kidney disease
Tests a low protein diet to slow kidney decline in adults with chronic kidney disease.
Key facts
- Who runs it
- Centre Hospitalier le Mans
- Where
- La Flèche and Le Mans, FranceSee the 2 sites
- Trial code
- Registry title
- Protecting Kidneys Through a Low Protein Diet: A Stepwise Multiple-Choice System Approach
- Status
- Recruiting
- People taking part
- 100 people, planned
- Started
- 1 Apr 2019
- Expected to end
- 1 Apr 2028
- Type of study
- Interventional, 2 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- low protein diet
- Record updated
- 1 July 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with advanced chronic kidney disease who are followed at the unit. It tests low protein diets.
- Age
- 18 years and older
- Sex
- All sexes
- Disease stage
- Kidney disease stage 4-5, or stage 3 with fast progression
Main reasons for not taking part
- Malnutrition
- Short life expectancy
- Pregnancy
- Cannot complete the free-consent form
- No healthcare coverage
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- All adult patients followed on the unit for advanced CKD, with Kidney disease stage 4-5 or stage 3 with fast progression and without contraindications
Who cannot take part
- Patients aged less than 18 years old
- Malnutrition or short life-expectancy
- Pregnant women,
- Incapacity to complete the free-consent form,
- Pateints refusing participation in the study,
- Patients without healthcare coverage
Where in France
- Pôle Santé Sarthe et LoirLa Flèche, FranceContact: Giorgina PICCOLI, PhDTaking people
- Centre Hospitalier Le MansLe Mans, FranceContact: Christelle Jadeau, PDTaking people
About the trial
What the trial wants to find out
Nephrology care continues to progress and recommendations are now focused on delaying as much as possible the need for renal replacement therapy ("intent-to-defer"strategy). Protein restriction is a valuable tool for stabilizing chronic kidney disease (CKD) and retarding the need for renal replacement therapy, but the best diet to be prescribed is still matter of discussion. This study is aimed at identifying implementation strategies for nutritional management of advanced CKD.
The 2 groups in the trial
- Diet groupTreatment being tested
Diet follow-up to personalize a low-protein diet for each patient. All patients following a low protein diet one month or more compose the "diet group".
Treatment: low protein diet
- Control groupNo study treatment, for comparison
Patients who accepted to take part of the study but refused the low protein diet and patients who discontinued the diet on the first month compose the control group.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Protecting Kidneys Through a Low Protein Diet: A Stepwise Multiple-Choice System Approach
- Plain-language title
- Tests a low protein diet to help protect kidneys in chronic kidney diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 1 July 2026