Studies past hospital records of people with acute heart failure or heart attack
Reviews records to find what triggers heart failure and how it progresses.
Key facts
- Who runs it
- University Hospital, Basel, Switzerland
- Where
- Basel, SwitzerlandSee the site
- Trial code
- Registry title
- Heart Failure-USB: Prediction and Progression
- Status
- Recruiting
- People taking part
- 6,000 people, planned
- Started
- 13 Jun 2019
- Expected to end
- 4 Apr 2027
- Type of study
- Observational, 2 groups
- Treatments tested
- medical chart review
- data generated by direct IT export
- Record updated
- 22 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who were in hospital with acute coronary syndrome or acute heart failure. Their health records will be reviewed.
- Age
- 18 Years and older
- Sex
- All sexes
- Disease stage
- Hospitalized with a main diagnosis of acute coronary syndrome (ACS), or with a main or secondary diagnosis of acute heart failure (AHF).
Main reasons for not taking part
- A documented statement by the patient against the scientific use of their clinical data
The registry criteria, word for word
Show all 3 criteriaShow less
Who can take part
- Patients hospitalized with a primary diagnosis of ACS
- Patients hospitalized with a primary or secondary diagnosis of AHF
Who cannot take part
- Existence of a documented statement of the patient against the scientific use of clinical data
Where in Switzerland
- Cardiology, University Hospital BaselBasel, SwitzerlandContact: Christian Mueller, Prof. Dr.Taking people
About the trial
What the trial wants to find out
This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.
The 2 groups in the trial
- acute coronary syndrome (ACS)
Outcome information (all-cause death, heart failure (HF) hospitalizations) of patients hospitalized with a primary diagnosis of ACS is analyzed.
Treatment: medical chart review and data generated by direct IT export
- acute heart failure (AHF)
Outcome information (all-cause death, heart failure (HF) hospitalizations) of patients hospitalized with a primary or secondary diagnosis of AHF is analyzed.
Treatment: medical chart review and data generated by direct IT export
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Heart Failure-USB: Prediction and Progression
- Plain-language title
- Studies past hospital records of people with acute heart failure or heart attackGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 22 September 2026