NCT04080492Terminated
A Cardiac Disease Quality of Life Study
A Prospective Study to Assess Multi-Domain Patient-Reported Cardiac Quality of Life in Adults With Hypertrophic Cardiomyopathy, Thoracic Aortopathy, and Radiation-Induced Heart Disease: UPLIFT
Source: ClinicalTrials.gov · Last updated 17 Sept 2026
Reason given: Enrollment goal not met
Brief summary (registry, in English)
A prospective, longitudinal, non-comparator, non-randomized observational cohort study to assess the quality of life in adult patients affected by hypertrophic cardiomyopathy and thoracic aortic dilatations who are not amenable to surgery, as well as those affected radiation-induced cardiac disease caused by radiation therapy.
- Status (registry)
- Terminated
- Study type
- Observational
- Enrollment
- 380 (actual)
- First submitted
- 4 Sept 2019
- Start date
- 26 Aug 2019
- Primary completion date
- 2 Sept 2022
- Lead sponsor
- The Cleveland Clinic
- Diseases
- Hypertrophic cardiomyopathy
- NCT number
- NCT04080492
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previously had surgery or plans to have surgery (full/mini sternotomy or endovascular) in the next nine months for HCM or TAD.
Other
- Inability or unwillingness to comply with study requirements in the opinion of the investigator.
- Inability to provide informed consent.
Who the study is looking for
- Patients aged 18-70 at time of consent with a confirmed diagnosis of HCM, TAD, and/or RIHD being seen at CC Main Campus for a comprehensive clinical cardiac evaluation (i.e. physician, surgeon, nurse practitioner, geneticist, testing, imaging, etc) to define treatment plan for either diagnosis as per Cleveland Clinic provider.
- Patient or an individual in their social support network has the equipment (phone, computer, tablet) and internet connection to complete the emailed follow-up questionnaires.
Age in the registry: 18 years to 70 years · Sex: All
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cleveland Clinic | Cleveland | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.