A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene

Criteria the registry did not label

• Main Inclusion Criteria:
• Male or female, ≥ 18 years of age.
• Clinical presentation consistent with adRP, based on ophthalmic examinations.
• Impairment on VF in the opinion of the Investigator, as determined by perimetry.
• A molecular diagnosis of autosomal dominant form of RP with the P23H mutation in the RHO gene, based on genetic analysis.
• A clear ocular media and adequate pupillary dilation to permit good quality fundus imaging, as assessed by the Investigator.
  • Main Exclusion Criteria:
• Presence of additional pathogenic mutations in genes (other than the P23H mutation in the RHO gene) associated with inherited retinal degenerative diseases or syndromes, based on genetic analysis (eg, Usher syndrome, Leber congenital amaurosis, etc).
• Presence of any significant ocular or non-ocular disease/disorder (including medication and laboratory test abnormalities) which, in the opinion of the Investigator and with concurrence of the Medical Monitor, may either put the subject at risk because of participation in the study, may influence the results of the study, or the subject's ability to participate in the study.