NCT04129021Recruiting
High Resolution, High-speed Multimodal Ophthalmic Imaging
High Resolution and High Speed Multimodal Ophthalmic Imaging
Source: ClinicalTrials.gov · Last updated 18 Nov 2025
Brief summary (registry, in English)
Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems are limited in resolution, speed, or access to certain structures of the eye. The use of a high-resolution imaging system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many microstructures of the eye: photoreceptors, vessels, nerve bundles in the retina, cells and nerves in the cornea. The use of a high-speed acquisition imaging system makes it possible to detect functional measurements such as the speed of blood flow. The combination of data from multiple imaging systems to obtain multimodal information is of great importance for improving the understanding of structural changes in the eye during a disease. The purpose of this project is to observe structures that are not detectable with routinely used systems.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 1200 (estimated)
- First submitted
- 19 Aug 2019
- Start date
- 3 Jul 2019
- Primary completion date
- Jul 2027
- Lead sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
- NCT number
- NCT04129021
What you commit to
- Study type: Interventional
- Planned participants: 1200
- From 3 Jul 2019 to the primary completion date, Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have just received a photodynamic therapy treatment (
- Patients taking drugs with photosensitivity as a side effect.
Other illness
- Patients with a history of photosensitivity.
- Patients with viral conjunctivitis or any other infectious disease.
- Patients at high risk of damage from optical radiation, such as aphakic patients, or patients with decreased sensitivity to light due to fundus disease.
Other
- Persons with pacemakers or other implanted electronic medical device
- Patients with skin lesions on the neck or forehead
- Pregnant or lactating women
- Participant unable to be followed throughout the study
- Vulnerable people
- Subjects with predisposition to closure of the iridocorneal angle
Who the study is looking for
- People over 18
- Patient with a pathology affecting the eye or healthy volunteer
- Participant who signed the consent
- Beneficiaries of the health insurance
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier National D'ophtalmologie Des Quinze Vingts Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.