Testing in vitro maturation of eggs in women with polycystic ovary syndrome
Tests a low-cost egg maturation method for IVF in women with polycystic ovary syndrome.
Key facts
- Who runs it
- Bruce Rose, MD
- Where
- Jacksonville, United StatesSee the site
- Trial code
- Registry title
- IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
- Status
- Recruiting
- People taking part
- 300 people, planned
- Started
- 10 May 2019
- Planned end
- 31 Dec 2023
- Type of study
- Interventional
- Treatments tested
- in vitro maturation of oocytes
- Record updated
- 4 November 2019
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 18 to 38 with a polycystic ovary (PCO) pattern who are having IVF with in vitro maturation (IVM) of eggs.
- Age
- 18 to 38 years
- Sex
- Women only
- Disease stage
- Polycystic ovary (PCO) pattern with more than 25 antral follicles; AMH above 3.5.
- Biomarker or test result
- AMH above 3.5
Main reasons for not taking part
- BMI above 35
- Body shape that makes egg retrieval through the vagina difficult or impossible
- A medical condition that makes pregnancy or IVF risky
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- PCO pattern with > 25 antral follicles
- AMH > 3.5
Who cannot take part
- complicating medical condition making pregnancy or IVF relatively contra-indicated
- BMI > 35
- body morphology making transvaginal retrieval difficult or impossible
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 38 years old?
Where in United States
- Brown FertilityJacksonville, United StatesContact: Julius Varzoni, BSTaking people
About the trial
What the trial wants to find out
A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte environment during oocyte retrieval, use of oral medications and very low doses of FSH, and delayed embryo transfer during subsequent warmed cryo-preserved embryo transfer. Eligible patient have a PCO pattern in their ovaries during transvaginal ultrasound.
The group in the trial
- AllTreatment being tested
Patients requiring IVF treatment with PCOS or a PCO pattern in their ovaries who wish to undertake IVM (as a variant of their IVF procedure)
Treatment: in vitro maturation of oocytes
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Prospective Series of IVF Cases Utilizing in Vitro Maturation (IVM) With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Embryo Transfer Using a Subsequent Frozen Embryo Transfer Cycle
- Plain-language title
- Testing in vitro maturation of eggs in women with polycystic ovary syndromeGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT04149496, who can take part
- Record updated
- 4 November 2019