Comparing two laser surgery methods for ovarian endometrioma cysts
Compares two laser surgeries for ovarian cysts from endometriosis in women.
Plain-language title generated from the registry record
Registry title: Conservative Endometrioma Surgery
Key facts
- Where
- Antwerp, Brussels, Leuven, and Liège, BelgiumSee the 4 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 40 years old?
Source: NCT04151433, who can take part
Where in Belgium
- GZA Sint-AugustinusAntwerp, BelgiumTaking people
- Cliniques Universitaires Saint-Luc (UCL)Brussels, BelgiumTaking people
- UZLeuvenLeuven, BelgiumTaking people
- CHR La CitadelleLiège, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universitaire Ziekenhuizen KU Leuven
- Trial code
- NCT04151433
- Record updated
- 10 December 2024
- Original description
To study which surgical technique offers better results in treating endometriomas in terms of ovarian reserve preservation.Read full original descriptionShow less
BLAST: a Randomized Controlled Trial on Conservative Endometrioma Surgery Using the CO2 Laser: the Combined Technique Versus CO2 Laser Vaporization Only
To study which surgical technique offers better results in treating endometriomas in terms of ovarian reserve preservation.
The 2 conservatives techniques used are:
1. The combined technique 2. CO2 laser vaporization only
Ovarian reserve will be assessed by consecutive measurements of AMH serum levels before and after surgery.
Inclusion: Age: 18 - 40 years (both inclusive); Unilateral endometriotic cysts with a mean diameter of >=2.5cm and ≤8 cm, measured in 3 dimensions; Presence of a contralateral endometrioma of ≤ 2cm is allowed; Complaining of infertility and/or pain; BMI ≤35; Use of contraception (combined or Progesteron only) for at least 4 weeks before surgery.
Exclusion: Incomplete surgery for the pelvis; Prior unilateral oophorectomy; (History of) hysterectomy; Pituitary/hypothalamic disorders; Suspected malignancy; Contra-indication for the use of contraception (combined or Progesteron only); Use of GnRH analogues preoperatively and in the first 3 months postoperatively; Contralateral endometrioma of >2 cm; AMH <0.7 preoperatively; Pregnancy.
Population: patients planned for laparoscopic CO2 laser surgery for endometriotic cysts.