Genetic testing of embryos before transfer in women with infertility
Tests genetic screening of embryos before single embryo transfer in women with infertility.
Key facts
- Who runs it
- Genomic Prediction Inc.
- Where
- Margate, United StatesSee the site
- Trial code
- Registry title
- Preimplantation Genetic Testing in Women of Advanced Maternal Age
- Status
- Recruiting
- People taking part
- 240 people, planned
- Started
- 5 Mar 2021
- Expected to end
- Dec 2026
- Type of study
- Interventional, 2 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- Preimplantation genetic testing for aneuploidy (PGT-A)
- Record updated
- 26 August 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 35 to 40 who are having IVF with ICSI (sperm injected into the egg). It compares transferring one genetically tested embryo with one untested embryo.
- Age
- 35 to 40 years at the start of the IVF cycle
- Sex
- Women only
- Disease stage
- Female infertility, with IVF using ICSI. Any ovarian stimulation protocol is allowed. Sperm can be from ejaculation or from the testicle, from the partner or a donor.
Main reasons for not taking part
- Polycystic ovary syndrome (PCOS) without ovulation
- Using donor eggs
- Using a gestational carrier (another woman carries the pregnancy)
- Recurrent pregnancy loss: 3 or more miscarriages in a row
- Recurrent implantation failure: 3 or more failed embryo transfers
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Women undergoing IVF of between 35 and 40 years of age at IVF cycle start
- Utilization of Intracytoplasmic Sperm Injection ICSI
- Utilization of ejaculated or testicular sperm
- Utilization of autologous or donor sperm
- All Controlled Ovarian Hyperstimulation (COH) protocols
Who cannot take part
- Patients with anovulatory Polycystic ovarian syndrome (PCOS)
- Recurrent Implantation Failure (RIF) defined as ≥ 3 more failed embryo transfers
- Utilization of donor oocytes
- Utilization of gestational carrier
- Recurrent Pregnancy Loss (RPL) defined as ≥ 3 consecutive miscarriages
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 35 and 40 years old?
Where in United States
- IVF Florida Reproductive AssociatesMargate, United StatesContact: Clinial ResearchTaking people
About the trial
What the trial wants to find out
The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo transfer in women between 35 and 40 years of age.
The 2 groups in the trial
- PGT-A transferTreatment being tested
Transfer of single chromosomally normal (euploid) blastocyst after PGT-A
Treatment: Preimplantation genetic testing for aneuploidy (PGT-A)
- Untested blastocyst transferNo study treatment, for comparison
Transfer of single untested blastocyst based on embryo morphology criteria.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- GEnetic Testing in Elective Single Embryo Transfer in Women of Advanced Maternal Age
- Plain-language title
- Genetic testing of embryos before transfer in women with infertilityGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 15 November 2026.
- Fit questions
- Built from NCT04167748, who can take part
- Record updated
- 26 August 2025