NCT04191655Completed
High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD)
Source: ClinicalTrials.gov · Last updated 6 Mar 2026
Brief summary (registry, in English)
Inflammatory Bowel Disease (IBD) involving the colon is a known risk for colon cancer. There are two standards-of-care colonoscopy techniques used for screening all patients who suffer from IBD for more than eight years. One method is to obtain random biopsies throughout the colon and the other is by using dye spraying chromo-colonoscopy. This trial aims to study the difference between the two colonoscopy techniques during the era of high definition camera in detecting neoplastic lesions during screening patients with long-standing IBD.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 211 (actual)
- First submitted
- 2 Dec 2019
- Start date
- 3 Apr 2019
- Primary completion date
- 1 Jan 2024
- Lead sponsor
- Beth Israel Deaconess Medical Center
- NCT number
- NCT04191655
What you commit to
- Study type: Interventional
- Participants enrolled: 211
- From 3 Apr 2019 to the primary completion date, 1 Jan 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior colonoscopy within the last 6 months
Other illness
- History of colorectal cancer
- History of total colectomy
- Allergy to dye spray
Other
- Poor bowel preparation
- Unable to provide informed consent
- Severe inflammation preventing visualization of the mucosa during the procedure.
Who the study is looking for
- Patient age ≥18yr old
- History of UC or colonic Crohn's disease or unclassified colitis patients with or without colonic adenoma history
- Duration of ≥ eight years since diagnosis, or any duration with a diagnosis of primary sclerosing cholangitis
- Mucosal lesion involves ≥ 1/3 of the colon
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Beth Israel Deaconess Medical Center Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Lahey Hospital and Medical Center Coordinator of this site? Confirm its status | Burlington | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.