Effect of Acupuncture on Quiescent Crohn's Disease

Other illness

• patients with serious organic diseases;
• patients who take antibiotics, probiotics, traditional Chinese medicine and other drugs at the same time, or who suffer from multiple diseases and need to take other drugs for a long time, and may affect the observation of the efficacy of this trial;
• severe skin diseases (such as erythema nodosum, pyoderma gangrenosum, etc.), eye diseases (such as iritis, uveitis, etc.), thromboembolic diseases and other serious extraintestinal manifestations;
• there are serious intestinal fistula, abdominal abscess, intestinal stenosis and obstruction, perianal abscess, gastrointestinal hemorrhage, intestinal perforation and other complications;
• patients with short bowel syndrome who have undergone abdominal or gastrointestinal surgery in the past half a year;
• there are skin diseases or defects in the selected area of acupuncture and moxibustion that cannot be performed.

Other

• patients who are recently pregnant or in pregnancy or lactation;
• patients diagnosed as psychosis;

• aged 16-70;
• Patients with disease in remission: CDAI \<150 and at least one of the following: serum C-reactive protein \<5mg/L, fecal calprotectin \<50μg/g or no ulcers on endoscopy;
• Patients with more than 2 disease relapses in the past year;
• patients were not taking medication or were only taking one or more of the following drugs: \[prednisone ≤15mg/d, azathioprine (≤1mg/kg/d), methotrexate (≤15mg/w) or mesalazine (≤4g/d)\] and prednisone was used for at least 1 month, while azathioprine, methotrexate or mesalazine was used for at least 3 months;
• those who did not use anti-TNF alpha and other agents within 3 months before entering the study;
• those who have never experienced acupuncture;
• patients signing informed consent.