Tests clearing clot during heart attack angioplasty in people with large clots
Tests manual clot suction during angioplasty in adults with a heart attack and large clots.
Plain-language title generated from the registry record
Registry title: Thrombus Aspiration in STEMI Patients With High Thrombus Burden
Key facts
- Where
- Changsha, Chengdu, Foshan, Fuzhou, Ganzhou, Guangzhou, Guilin, Haikou, Huizhou, Jiangmen, Kaiping, Kashgar, Kunming, Maoming, Shantou, Shaoguan, Shaoxing, Shenzhen, Taishan, Ürümqi, Weifang, Wenzhou, Wuhan, Xi’an, Xiongzhou, Yangjiang, Zhanjiang, Zhaoqing, Zhongshan, and Zhuhai, ChinaSee the 50 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults having a heart attack (STEMI) who get an emergency stent procedure within 12 hours of symptoms and have a large blood clot in the artery.
- Age
- 18 years and older
- Sex
- All sexes can join
- Disease stage
- Heart attack with ST-segment elevation (STEMI), treated with primary PCI within 12 hours after symptoms began. High clot burden (TIMI thrombus grade ≥3) seen after the guidewire passes the narrowed spot.
- Earlier treatment
- People who already had clot-dissolving (thrombolytic) treatment cannot join. People who had coronary artery bypass surgery cannot join.
Main reasons for not taking part
- Unstable blood circulation or cardiogenic shock
- Clot-dissolving (thrombolytic) treatment already given
- Expected survival under 6 months because of a non-heart disease
- Earlier coronary artery bypass surgery
- Bleeding in the stomach or bowel before the procedure, or a reason not to take dual antiplatelet therapy
Read by machine on 12 November 2026.
Where in China
- The Second Xiangya Hospital of Central South UniversityChangsha, ChinaContact: Xinqun Hu, MDNot yet recruiting
- The Third Xiangya Hospital of Central South UniversityChangsha, ChinaContact: Yu Cao, MDTaking people
- Sichuan Provincial People's HospitalChengdu, ChinaContact: Jianhong TaoNot yet recruiting
- West China HospitalChengdu, ChinaContact: Yong He, MDNot yet recruiting
- First People's Hospital of FoshanFoshan, ChinaContact: Xili YangTaking people
- First People's Hospital of Shunde (Affiliated Hospital at Shunde, Southern Medical University)Foshan, ChinaContact: Yunzhao HuTaking people
- The Second People's Hospital of Nanhai DistrictFoshan, ChinaContact: Pengcheng He, MDTaking people
- Fujian Provincial HospitalFuzhou, ChinaContact: Wei ChenNot yet recruiting
- GanZhou Municopal HospitalGanzhou, ChinaContact: Zhonghan NiNot yet recruiting
- Shangyou HospitalGanzhou, ChinaContact: Shuo SunTaking people
- Guangdong Provincial Hospital of Traditional Chinese MedicineGuangzhou, ChinaContact: Xia WangNot yet recruiting
- Guangdong Provincial People's HospitalGuangzhou, ChinaContact: Pengcheng He, MDTaking people
- Guangzhou General Hospital of Guangzhou Military CommandGuangzhou, ChinaContact: Dingcheng Xiang, MDNot yet recruiting
- Guangzhou Panyu Central HospitalGuangzhou, ChinaContact: Jianhao LiNot yet recruiting
- Huadu District People's Hospital of GuangzhouGuangzhou, ChinaContact: Junhui XiaoNot yet recruiting
- Huangpu Division of The First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, ChinaContact: Qing XuNot yet recruiting
- Nanfang HospitalGuangzhou, ChinaContact: Jianping Bin, MDNot yet recruiting
- The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, ChinaContact: Zheng Huang, MDNot yet recruiting
- The First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, ChinaContact: Yi Li, MDNot yet recruiting
- The Second Affiliated Hospital, Sun Yat-Sen UniversityGuangzhou, ChinaContact: Ruqiong NieNot yet recruiting
- Zhujiang Hospital of Southern Medical UniversityGuangzhou, ChinaContact: Hua XiaoNot yet recruiting
- Guilin People's HospitalGuilin, ChinaContact: Bin LiNot yet recruiting
- Hainan People's HospitalHaikou, ChinaContact: Bin LiNot yet recruiting
- The Second Clinical College of Hainan Medical UniversityHaikou, ChinaContact: Yuewu ChenNot yet recruiting
- Huizhou Third People's HospitalHuizhou, ChinaContact: Sigan ZhongNot yet recruiting
- Jiangmen Central HospitalJiangmen, ChinaContact: Gaoxing Zhang, MDTaking people
- Kaiping Central HospitalKaiping, ChinaContact: Pengcheng He, MDTaking people
- Kashgar first people's HospitalKashgar, ChinaContact: Yuying HuTaking people
- Yan'an Hospital of Kunming CityKunming, ChinaContact: Qiang Xue, MDNot yet recruiting
- Maoming people's hospitalMaoming, ChinaContact: Chunbo Chen, MDNot yet recruiting
- The Second Affiliated Hospital Of Shantou University Medical CollegeShantou, ChinaContact: Jilin Li, MDTaking people
- Yue Bei People's HospitalShaoguan, ChinaContact: Liangqiu TangTaking people
- Shaoxing People's HospitalShaoxing, ChinaContact: Yangjian LiuNot yet recruiting
- Peking University Shenzhen HospitalShenzhen, ChinaContact: Chun Wu, MMNot yet recruiting
- Shenzhen Bao'an District People's HospitalShenzhen, ChinaContact: Zhiming ShenTaking people
- Shenzhen People's HospitalShenzhen, ChinaContact: Huadong Liu, MDTaking people
- The Eighth Affiliated Hospital, Sun Yat-Sen UniversityShenzhen, ChinaContact: Guifu Wu, PDTaking people
- Taishan people's HospitalTaishan, ChinaContact: Yan ChenTaking people
- The First Affilicated Hospital of Xinjiang Medical UniversityÜrümqi, ChinaContact: Yining Yang, MDNot yet recruiting
- Affiliated Hospital, Weifang Medical UniversityWeifang, ChinaContact: Jingtian LiTaking people
- The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, ChinaContact: Hao ZhouNot yet recruiting
- Wuhan Asia Heart HospitalWuhan, ChinaContact: Hua Yan, MDNot yet recruiting
- The First Affiliated Hospital of Xi'an Jiaotong UniversityXi’an, ChinaContact: Ning GuoNot yet recruiting
- Nanxiong people's HospitalXiongzhou, ChinaContact: Foyuan FanTaking people
- People's Hospital of Yangjiang CityYangjiang, ChinaContact: Jiaman OuTaking people
- The Second Affiliated Hospital of Guangdong Medical UniversityZhanjiang, ChinaContact: Can ChenNot yet recruiting
- Sihui people's HospitalZhaoqing, ChinaContact: Yuehua HuangTaking people
- Zhongshan People's HospitalZhongshan, ChinaContact: Li FengTaking people
- The Fifth Affiliated Hospital Sun Yat-sen UniversityZhuhai, ChinaContact: Jian Chen, MDNot yet recruiting
- Zhuhai People's HospitalZhuhai, ChinaContact: Jun LiNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Guangdong Provincial People's Hospital
- Trial code
- NCT04212494
- Record updated
- 9 September 2026
- Original description
This is a prospective, multicenter, open-label, randomized, controlled, parallel group study, in which ST-segment Elevation Myocardial Infarction (STEMI) patients with high thrombus burden(TIMI thrombus grade ≥3) are included. Patients are randomized to be treated with or without manual thrombus aspiration(TA) during primary percutaneous coronary intervention(PPCI) by a ratio of 1:1.Read full original descriptionShow less
Thrombus Aspiration in Primary Percutaneous Coronary Intervention for STEMI Patients With High Thrombus Burden
This is a prospective, multicenter, open-label, randomized, controlled, parallel group study, in which ST-segment Elevation Myocardial Infarction (STEMI) patients with high thrombus burden(TIMI thrombus grade ≥3) are included. Patients are randomized to be treated with or without manual thrombus aspiration(TA) during primary percutaneous coronary intervention(PPCI) by a ratio of 1:1.
Inclusion: Age ≥ 18 years; STEMI patients undergoing primary PCI within 12 hours after the onset of symptoms; High thrombus burden after guidewire passes the lesion (TIMI thrombus grade ≥3); Informed consent must be voluntary.
Exclusion: After thrombolytic therapy; The predicted survival time is less than 6 months due to non-cardiac disease; History of coronary artery bypass grafting; Preoperative gastrointestinal bleeding or contraindications to dual antiplatelet therapy; Haemodynamic instability or cardiogenic shock; Participate in other researches within 30 days; Patients were considered unsuitable by other researchers.