Taking people in SwitzerlandNo phase

Following People With Eczema and Related Allergic Diseases Over Time

Observes people with atopic dermatitis and asthma, collecting clinical and laboratory data over time.

Key facts

Who runs it: University of Zurich
Where: Zurich, SwitzerlandSee the site
Trial code: NCT04240522
Registry title: Prospective Longitudinal Observational Research in Atopic Dermatitis
Status: Recruiting
People taking part: 1,000 people, planned
Started: 4 Apr 2017
Expected to end: 30 Mar 2031
Type of study: Observational
Record updated: 5 February 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people with atopic dermatitis or another allergic (atopic) disease, and also healthy people with no allergic disease. It is an observational study that collects clinical and lab data.

Age: 0 - 85 years (the registry also lists a minimum age of 1 Year)
Sex: All sexes can join.
Disease stage: Atopic dermatitis and/or another atopic disease, such as allergic rhinitis, allergic asthma or food allergy.
Earlier treatment: Current treatment does not matter. Everyone stays on the treatment that is medically needed.

Main reasons for not taking part

Unable to give consent
Refusing to take part in the study

The registry criteria, word for word

Show all 7 criteriaShow less

Who can take part

Age 0 - 85 years
Diagnosis of AD and/or another disease of the atopic group (i.e. allergic rhinitis, allergic asthma, food allergy)
The inclusion of patients in this study is independent from the current therapy. During the study all patients will be kept on a therapy that is medically indicated; The inclusion criteria for healthy controls in this study are as follows:
Age 0 - 85 years
No diagnosis or history of allergic disease
The inclusion of patients in this study is independent from the current therapy. During the study all patients will be kept on a therapy that is medically indicated; Written consent will be obtained after detailed information of the study was given to the participant

Who cannot take part

Unable to give consent or refusal to participate in the study

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

Are you between 1 and 85 years old?

Where in Switzerland

Allergy Unit, Dept. of Dermatology, Unviersity Hosptial of ZurichZurich, SwitzerlandContact: Marie-Charlotte Brueggen, Prof, MDTaking people

About the trial

What the trial wants to find out

Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within a few years. This sequence is called atopic march.

Read full original descriptionShow less

Atopic dermatitis and associated atopic diseases are more frequent in families, suggesting a genetic predisposition. However, the underlying factors such as genetic phenotype, environmental factors, or life style which cause or worsen an existing allergic disease are not understood yet. Affected people suffer from recurrent flares that result in significantly impaired quality.

This study will collect clinical and laboratory data to elucidate immunotolerance and preventiv stategies with the aim to develop new and individual treatment options of atopic diseases.