Studying inflammation in fat tissue from people with obesity
Tests whether added resolution molecules calm inflammation in fat tissue from adults with obesity.
Plain-language title generated from the registry record
Registry title: Adipose Inflammation and Diabetes (FAB)
Key facts
- Where
- Gothenburg, SwedenSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT04255264, who can take part
Where in Sweden
- Sahlgrenska University HospitalGothenburg, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Göteborg University
- Trial code
- NCT04255264
- Record updated
- 6 May 2025
- Original description
The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.Read full original descriptionShow less
Adipose Tissue Inflammation and Diabetes Development (Fettvävsinflammation Och Diabetesutveckling)
The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.
Inclusion: BMI 30-40 kg/m2; Ptos (i.e. excess skin) > 3 cm; Patient underwent gastric bypass surgery >2 years ago; Patient has had a stable weight ≥6 months at the time of operation; Patient does not smoke (min 6 weeks prior to surgery).
Exclusion: Preoperatively known hernia requiring surgical operation; Neurological, orthopedic or rheumatologic injury or illness affecting physical ability; Severe mental illness; Patients who do not understand spoken and written Swedish; American Society of Anesthesiologists (ASA) classification ≥ 3.