Proximal Row Carpectomy vs Four-corner Fusion for Osteoarthritis of the Wrist
Key facts
- Where
- Helsinki, Jyväskylä, Kotka, Tampere, and Turku, FinlandSee the 5 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT04260165, who can take part
Where in Finland
- Töölö Hospital (Helsinki University Hospital)Helsinki, FinlandContact: Samuli Aspinen, M.D., Ph.D.Taking people
- Central Hospital of Central FinlandJyväskylä, FinlandContact: Teemu Karjalainen, MD, PhDNot yet recruiting
- Kymenlaakso Central HospitalKotka, FinlandContact: Kaj Zilliacus, MDNot yet recruiting
- Tampere University HospitalTampere, FinlandContact: Veera Pikkarainen, MDNot yet recruiting
- Turku University HospitalTurku, FinlandContact: Hanna-Stiina Taskinen, MD, PhDNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Töölö Hospital
- Trial code
- NCT04260165
- Record updated
- 19 January 2021
- Original description
Study purpose is to compare the outcome after proximal row carpectomy (PRC) vs four-corner fusion (FCA) for SLAC/SNAC II-III type osteoarthritis (OA) in a double-blinded randomized controlled study setting.Read full original descriptionShow less
A Double-blinded Randomized Controlled Multicenter Trial Comparing Proximal ROw carpectOmy and Four-corner Fusion (PROOF) for Osteoarthritis of the Wrist
Study purpose is to compare the outcome after proximal row carpectomy (PRC) vs four-corner fusion (FCA) for SLAC/SNAC II-III type osteoarthritis (OA) in a double-blinded randomized controlled study setting.
Patients with radiologically and clinically confirmed OA are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo either PRC or FCA. The study will be patient and assessor blinded.
Baseline data is collected preoperatively and is followed by a follow-up visits at 2 and 6 weeks, 3, 6, 12 months, and 5, 10 years after the intervention. Unveiling of the allocation is at 12 months post-intervention.
Inclusion: SLAC/SNAC II-III; Age 18 - 75; Symptom duration > 3 months; American Society of Anaesthesiologists physical status (ASA) I-II.
Exclusion: Alcohol or drug abuse; Condition or medication affecting bony healing (eg diabetes mellitus with poor glycemic control, malnutrition, use of per oral corticosteroids); Neurological condition affecting upper limb function; Age <18 or >75 years; Patient eligible for SL reconstruction or scaphoid; Ulnocarpal/pancarpal arthritis; Lunate fossa, proximal lunate arthrosis or both; Rheumatoid arthritis; Heavy smoking (> 20 cigarettes per day).