NCT04285398Active, not recruiting
Prospective Natural History Study of Retinitis Pigmentosa
Natural History Study of Retinitis Pigmentosa Due to RHO, PDE6a or PDE6b Mutations
Source: ClinicalTrials.gov · Last updated 22 May 2025
Brief summary (registry, in English)
This is natural history study of rods and cones degenerations in patients with Retinitis Pigmentosa (RP) caused by pathogenic mutations in RHO, PDE6a or PDE6b gene mutations.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 82 (actual)
- First submitted
- 24 Feb 2020
- Start date
- 12 Feb 2020
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- SparingVision
- Diseases
- Retinitis pigmentosa
- NCT number
- NCT04285398
What you commit to
- Study type: Interventional
- Participants enrolled: 82
- From 12 Feb 2020 to the primary completion date, 30 Jun 2026
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with other ocular disorder likely to impact the retinal function
Other
- Patients with any other gene mutation known to be involved in RP
- Pregnant or breastfeeding women
Who the study is looking for
- RP with mutations affecting the RHO, PDE6A and PDE6B genes
- Visual acuity ≥ 20/200 for at least one eye at inclusion visit
- Binocular Visual field diameter ≥ 5° as measured on the Goldmann III-4e isopter at inclusion visit
- Patients having signed the informed consent form
- Sufficient knowledge of the local language to ensure understanding of the tasks to be performed and the instructions received
- Patient affiliated to a Health Security System if they are included in a clinical site based in France (per law)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHNO XV-XX Paris - CIC 1423 Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| UPMC Eye Center Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.