NCT04306939Suspended
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
Source: ClinicalTrials.gov · Last updated 7 Jan 2026
Reason given: Suspended for analysis and to consider further enrollment.
Brief summary (registry, in English)
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect clinical decision making. The study will evaluate risk factors and co-variants, including genetic variants that are associated with disease progression such as pain, inflammation, organ dysfunction, disability and quality of life.
- Status (registry)
- Suspended
- Study type
- Observational
- Enrollment
- 120000 (estimated)
- First submitted
- 16 Dec 2019
- Start date
- 1 Nov 2014
- Primary completion date
- Dec 2026
- Lead sponsor
- University of Pittsburgh
- Diseases
- Crohn's disease, Fatty liver disease (MASLD/MASH), Rheumatoid arthritis, Multiple sclerosis, Chronic kidney disease, Cystic fibrosis
- NCT number
- NCT04306939
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Chronic infectious disease as the primary medical problem
Age
- Less than 12 years of age
Other
- Inability of the subject to understand the protocol
- Inability to the subject provide informed consent
Who the study is looking for
- Case Subjects
- Clinical diagnosis of a chronic disease or disorder (ex. pancreatitis, hepatitis or fatty liver, inflammatory bowel disease, irritable bowel syndrome, diarrhea, constipation, chronic pain syndromes, diabetes, hypertension, cardiovascular disease, chronic kidney disease, chronic neurologic disorders, rheumatological disorders, endocrine disorders, chronic pulmonary diseases, sinorespiratory disorders, chronic skin diseases, cancers and related disorders)
- Ability to read and write in English;
- Ability to provide informed consent
- Control Subjects
- UPMC patients age 12 years without a chronic disorder.
Age in the registry: 12 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pittsburgh Medical Center | Pittsburgh | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.