Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry
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Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT04310644, who can take part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- RWTH Aachen University
- Trial code
- NCT04310644
- Record updated
- 4 February 2025
- Original description
We examine patients with different autonomic neuropathies and Ehlers Danlos syndromes compared to healthy controls at three different points over time (baseline, after 3 months and after 1.5 years) to gain knowledge about the course of this disease and understand its pathophysiology, with a focus on Small Fiber neuropathy. Moreover we will validate the german version of the Malmö POTS Score and establish an easy diagnostic scheme for patients in outpatient care.Read full original descriptionShow less
Autonomic Neuropathy and Its Pathophysiology in Autoimmune Autonomic Neuropathies, Postural Orthostatic Tachycardia Syndrome and Ehlers Danlos Syndromes: Peripheral Autonomic Small Fiber Neuropathy or Central Autonomic Failure? Validation of the Malmö POTS Score and a Better Diagnosis of POTS in Patientes With Autnomic Failure (VaGeMAPS-3-step-Diag)
We examine patients with different autonomic neuropathies and Ehlers Danlos syndromes compared to healthy controls at three different points over time (baseline, after 3 months and after 1.5 years) to gain knowledge about the course of this disease and understand its pathophysiology, with a focus on Small Fiber neuropathy. Moreover we will validate the german version of the Malmö POTS Score and establish an easy diagnostic scheme for patients in outpatient care.
Inclusion: autonomic neuropathy; Postural orthostatic tachycardia syndrome; hypermobile or classical Ehlers Danlos syndromes; Chronic fatigue syndrome, mast cell activation syndrome and/or PostCOVID; healty controls; between 18-80 years; in patients: diagnosis and clinical testing in our outpatient clinic; German speaking.
Exclusion: neurodegenerative disease; pregnancy; Pacemaker or Deep brain Stimulation; sensory or motor Polyneuropathy.