Combining MyoCI Training With Memory Reactivation for Stroke Arm Recovery
Tests MyoCI arm training with memory reactivation during sleep in chronic stroke survivors.
Plain-language title generated from the registry record
Registry title: Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Key facts
- Where
- Chicago, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 100 years old?
Source: NCT04312269, who can take part
Where in United States
- Northwestern UniversityChicago, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Northwestern University
- Trial code
- NCT04312269
- Record updated
- 27 May 2026
- Original description
This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.Read full original descriptionShow less
Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.
Inclusion: Age at enrollment is 21 or older; Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening; Severe to moderate motor impairment (FMA-UE of 7-40); At least some voluntary shoulder and elbow muscle activation.
Exclusion: Ferromagnetic implants that are MRI incompatible; Visual impairment (such as hemianopia) preventing full view of screen; Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest); Inability to follow instructions of the MyoCI task; Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study; Inability to understand or follow commands in English due to aphasia or other reason; Diffuse or multifocal infarcts in both hemispheres; Substantial arm pain preventing participation for 90 minutes a day; Spasticity treatment (pharmacological or Botox) within last 3 months.