Comparing Two Lymph Node Removal Methods for Left Colon Cancer
Compares two extents of lymph node removal during surgery for left-sided colon cancer.
Plain-language title generated from the registry record
Registry title: D2 vs D3 Lymph Node Dissection for Left Colon Cancer
Key facts
- Where
- Moscow, RussiaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT04364373, who can take part
Where in Russia
- Clinic of coloproctology and minimally invasive surgeryMoscow, RussiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Russian Society of Colorectal Surgeons
- Trial code
- NCT04364373
- Record updated
- 17 August 2026
- Original description
The efficiency of the D3 lymph node dissection is still controversial for left colon cancer patients. This study will try find difference in 5-year overall survival between D2 and D3 lymph node dissection. Investigation of the functional and short-term outcomes will clarify safety of the D3 lymph node dissection.Read full original descriptionShow less
D2 vs D3 Lymph Node Dissection for Left Colon Cancer: Multicenter Randomize Control Trial (DILEMMA)
The efficiency of the D3 lymph node dissection is still controversial for left colon cancer patients. This study will try find difference in 5-year overall survival between D2 and D3 lymph node dissection. Investigation of the functional and short-term outcomes will clarify safety of the D3 lymph node dissection.
Inclusion: Agreement of the patient to participate in trial; Colon cancer (only adenocarcinoma ); The tumor located between the splenic flexure and rectosigmoid junction; cT3-Т4а,b; cN0-2; cM0; Tolerance of chemotherapy; ASA 1-3.
Exclusion: Previous radiotherapy or chemotherapy; Preoperative complications of the tumor (perforation and full bowel 3. obstruction); сТis - Т2, сТ4b (tail of the pancreas, stomach, small bowel, ureter, urinary bladder); Synchronous or metachronous tumors; Women during Pregnancy or breast feeding period.