NCT04370899Recruiting
Early Detection of Familial Hypercholesterolemia in Children
Early Detection of Familial Hypercholesterolemia in Children in Tarragona Province
Source: ClinicalTrials.gov · Last updated 18 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Heterozigous FH is an underdiagnosed disease in the paediatric population. Its early detection, would allow us to initiate lifestyle therapeutical changes and early pharmacological therapy if necessary. This is a key fact to reduce atherosclerosis progression and cardiovascular risk in adulthood. Moreover, it will allow, detecting the first and second degree affected relatives.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 400 (estimated)
- First submitted
- 28 Feb 2020
- Start date
- 14 Mar 2013
- Primary completion date
- 14 Mar 2030
- Lead sponsor
- Institut Investigacio Sanitaria Pere Virgili
- Diseases
- Familial hypercholesterolaemia
- NCT number
- NCT04370899
What you commit to
- Study type: Observational
- Planned participants: 400
- From 14 Mar 2013 to the primary completion date, 14 Mar 2030
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- The child population under 2 and over the age of 18 and children.
Other
- Children with high cholesterol but by secondary causes.
Who the study is looking for
- Children between 2 and 18 years of age.
- LDL-C level above 135 mg/dL
- Previously, the pediatrician will have discarded secondary causes (hypercholesterolaemia such as hypothyroidism, nephrotic syndrome, diabetes, renal insufficiency).
- After confirmation that one of the parents has a genetic mutation (Lipoxip/Liponext) or clinical diagnosis (DLCN ≥ 8), the child will be studied. The progenitor with hypercholesterolemia will be considered as an index case, in this way we will demonstrate the vertical transmission of the genetic disease.
Age in the registry: 2 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Universitari Sant Joan de Reus Coordinator of this site? Confirm its status | Reus | Spain | Recruiting |
| Hospital Universitari Sant Joan Coordinator of this site? Confirm its status | Reus | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.