Tests moderate aerobic exercise training in adults with persistent asthma
Tests whether moderate aerobic exercise helps adults with persistent asthma.
Plain-language title generated from the registry record
Registry title: SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training
Key facts
- Where
- Liège, BelgiumSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 65 with asthma that is not well controlled, who are on stable asthma treatment. It studies the effect of regular moderate exercise training.
- Age
- 18 to 65 years
- Sex
- All sexes can join.
- Disease stage
- Persistent asthma with an ACQ score above 1.5 (asthma not well controlled).
- Earlier treatment
- Must be on stable background treatment with at least one inhaled corticosteroid or an anti-leukotriene.
Main reasons for not taking part
- IMC above 35
- Severe osteoarthritis of the knees and hips
- Unstable angor
- Severe uncontrolled hypertension
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT04395937, who can take part
Where in Belgium
- CHU LiègeLiège, BelgiumContact: stephanie ziantTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Liege
- Trial code
- NCT04395937
- Record updated
- 14 April 2026
- Original description
The effects of regular exercise on asthma control has not yet been well demonstrated.Read full original descriptionShow less
SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training
The effects of regular exercise on asthma control has not yet been well demonstrated.
The aim of this study is to investigate the impact of submaximal aerobic training on exercise tolerance (VO2max - primary outcome) and a set of secondary outcomes: quality of life, asthma symptoms control, bronchial and systemic inflammatory markers, lung function, bronchial hyperresponsiveness, anxiety and depression and body composition in patients with persistant asthma.
Inclusion: asthmatic patient; aged 18- 65 years; ACQ > 1.5; stable background treatment comprising at least one inhaled corticosteroid or an anti-leukotriene.
Exclusion: Severe uncontrolled hypertension; IMC > 35; severe osteoarthritis of the knees and hips; unstable angor.