Tests a fermented food diet in adults with ulcerative colitis
Tests a fermented food diet against a regular diet in ulcerative colitis.
Plain-language title generated from the registry record
Registry title: Fermented Food-Supplemented Diet in Ulcerative Colitis
Key facts
- Where
- Palo Alto, United StatesSee the site
Where in United States
- Stanford UniversityPalo Alto, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Stanford University
- Trial code
- NCT04401605
- Record updated
- 27 February 2026
- Original description
The purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal inflammation. Fermented food have been shown to positively influence inflammatory cytokines and intestinal microbial diversity in healthy volunteers.Read full original descriptionShow less
Effects of a Fermented Food-Supplemented on Patients With Ulcerative Colitis
The purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal inflammation. Fermented food have been shown to positively influence inflammatory cytokines and intestinal microbial diversity in healthy volunteers.
Inclusion: Written informed consent; Male or female subjects, ≥18 years of age; Confirmed diagnosis of UC; Symptomatic disease defined as partial Mayo Score 2 to 7 (inclusive); Elevated fecal calprotectin.
Exclusion: Individuals diagnosed with a serious medical condition (unless approved in writing by a physician); Individuals who have been severely weakened by a disease or medical procedure; Individuals with more than mild-moderate cardiovascular disease or life-threatening cancer (as determined by patient's physician) unless approved by a physician; History of relevant intestinal surgery such as total or hemi-colectomy, proctocolectomy, stoma; Complications of disease such as extraintestinal manifestations (EIMs) are not automatically considered exclusion criteria. Appropriate medical treatment for UC and/or EIMs will not be withheld; Individuals with history of severe cardiac disease (particularly uncompensated congestive heart failure NYHA grade 2 or more or LVEF < 40%); Women who are pregnant, nursing or expect to be pregnant; Intolerance to fermented food; Individuals with a body mass index (BMI) lower than 18.