Registry and biobank collecting data on rheumatic diseases in adults
Collects health information and samples from adults with rheumatic diseases for research.
Key facts
- Who runs it
- Yale University
- Where
- New Haven, United StatesSee the site
- Trial code
- Registry title
- Rheumatology Patient Registry and Biorepository
- Status
- Recruiting
- People taking part
- 5,000 people, planned
- Started
- 4 Aug 2020
- Expected to end
- 1 Jun 2030
- Type of study
- Observational
- Record updated
- 13 February 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a rheumatic autoimmune disease who are treated at Yale Rheumatology clinics, and also healthy adult volunteers. It collects samples and information for research.
- Age
- 18 to 99 years
- Sex
- All sexes can join.
- Disease stage
- A rheumatic autoimmune disease, such as lupus, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, scleroderma or vasculitis. Healthy volunteers must have no such diagnosis.
Main reasons for not taking part
- Cannot give informed consent
- Allergy to lidocaine or epinephrine (cannot give a skin biopsy)
- History of impaired wound healing (cannot give a skin biopsy)
- Currently pregnant (must wait until after delivery to give a skin biopsy)
- Healthy volunteers: chronic skin conditions, or a rheumatic autoimmune disease, or a BMI that is not normal
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- Patients ≥18 years old with a diagnosis of a rheumatic autoimmune disease including, but not limited to: adult onset Still's disease, ankylosing spondylitis, antiphospholipid syndrome, Behcet's disease, dermatomyositis, giant cell arteritis, mixed connective tissue disease, polymyalgia rheumatica, polymyositis, psoriatic arthritis, reactive arthritis, rheumatoid arthritis, sarcoidosis, scleroderma, Sjogren's syndrome, systemic lupus erythematosus, undifferentiated connective tissue disease and vasculitis
- Receiving clinical care at Yale Rheumatology clinics
- Age ≥ 18 years old
- No chronic skin conditions
- No diagnosis of a rheumatic autoimmune disease (e.g., lupus, rheumatoid arthritis)
- Normal BMI
Who cannot take part
- Patients allergic to lidocaine or epinephrine or have a history of impaired wound healing will not be able to donate a skin biopsy
- Allergies to lidocaine or epinephrine (skin biopsies)
- A history of impaired wound healing (skin biopsies)
- Unable to provide informed consent
- No patients will be excluded based on gender or ethnicity or pregnancy status
- Women who are currently pregnant will need to wait to donate a skin biopsy until after they deliver
- Unable to provide informed consent
- Currently pregnant or nursing unless the study goal is to study pregnant or nursing woman
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 99 years old?
Where in United States
- Yale New Haven HospitalNew Haven, United StatesContact: Monique Hinchcliff, MD (principal investigator)Taking people
About the trial
What the trial wants to find out
To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.
The group in the trial
- Biorepository
Participants with rheumatic diseases who contributed biospecimen samples (blood, saliva, urine, stool, tissue).
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Rheumatology Patient Registry and Biorepository
- Plain-language title
- Registry and biobank collecting data on rheumatic diseases in adultsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT04402086, who can take part
- Record updated
- 13 February 2026