Macromolecular Imaging of White and Gray Matter Pathology in Multiple Sclerosis
Key facts
- Where
- Madison, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT04415372, who can take part
Where in United States
- University of Wisconsin - MadisonMadison, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Wisconsin, Madison
- Trial code
- NCT04415372
- Record updated
- 28 April 2026
- Original description
The overall purpose of this research is to determine whether new macromolecular measures optimized for whole brain (gray matter and white matter) magnetic resonance imaging (MRI), predict neuro-cognitive impairment in multiple sclerosis (MS) patients.Read full original descriptionShow less
The overall purpose of this research is to determine whether new macromolecular measures optimized for whole brain (gray matter and white matter) magnetic resonance imaging (MRI), predict neuro-cognitive impairment in multiple sclerosis (MS) patients.
Inclusion: Clinically definite MS; Adult age 18 to 60.
Exclusion: Changes in MS therapy in the last 6 months; Less than 6 weeks after relapse or corticosteroid use; Currently taking medication that may affect cognition (e.g. donepezil, rivastigmine, adderall); History of significant alcohol or drug abuse; Confounding neurological or cognitive disorders or deficits (stroke, Parkinson's disease, Alzheimer's disease, epilepsy); History of developmental or learning disability or attention-deficit/hyperactivity disorder.\; history of alcohol/drug abuse; history of migraines; developmental or learning disability/attention-deficit/hyperactivity disorder; Contraindication to MRI; Current or recent significant migraines; Sensory or physical impairments that might interfere significantly with cognitive testing; currently pregnant/breastfeeding.