Tests a herbal formula for eczema in children against a placebo
Tests a herbal granule formula against placebo for eczema in children aged 4 to 17.
Key facts
- Who runs it
- Chinese University of Hong Kong
- Where
- Hong Kong, Hong KongSee the site
- Trial code
- Registry title
- Evaluate the Efficacy of Using Modified Qing-Ying Decoction in Atopic Dermatitis Children
- Status
- Recruiting
- Phase
- Phase 2/3
- People taking part
- 64 people, planned
- Started
- 10 Sept 2020
- Expected to end
- Aug 2027
- Type of study
- Interventional, 2 groupsOne group gets a placebo (a dummy treatment), for comparison.
- Treatments tested
- Modified Qing-Ying Decoction
- Identical looking placebo
- Record updated
- 30 July 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for children and teenagers aged 4 to 17 with subacute or chronic atopic dermatitis (eczema). It tests a herbal granule drink against a placebo for 12 weeks.
- Age
- 4 to 17 years (Chinese only)
- Sex
- All sexes can join.
- Disease stage
- Subacute or chronic atopic dermatitis with dry, scaly, red bumps and patches on the skin. EASI score of 10 or more.
- Earlier treatment
- Must not have taken oral corticosteroids, oral antibiotics, other immunosuppressive drugs or oral herbal medicines for atopic dermatitis in the past month. Must not have taken anti-coagulant or anti-platelet drugs, probiotics or prebiotics in the past month.
Main reasons for not taking part
- Allergy to Chinese medicines
- Known bacterial skin infection
- Known pregnancy
- Severe heart, liver or kidney problems, or diabetes
- Known G6PD deficiency
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- Age of 4 to 17 (Chinese only)
- With EASI ≥ 10
- Subacute and chronic atopic dermatitis presenting with dry, scaly, erythematous papules and plaques; and
- Provide written informed consent form (signed by one of their parents)
Who cannot take part
- Having used oral corticosteroids, oral antibiotics, other immunosuppressive or any preparation of oral herbal medicines for the treatment of AD in the past month
- History of allergy to Chinese medicines
- AD with Yang deficiency in syndrome differentiation, such as pale looking, always feeling cold, fatigue, chronic diarrhea with loose stool, urinary disorders such as urinary difficulty, excessive urination or incontinence
- Known overt bacterial infections in the skin
- Known severe medical conditions, such as cardiovascular, liver or renal dysfunction or Diabetes Mellitus
- Having been diagnosed with scabies, allergic contact dermatitis, seborrheic dermatitis or psoriasis; and
- Has taken anti-coagulant or anti-platelet drugs in the past month
- Known history of glucose-6-phosphate dehydrogenase (G6PD) deficiency
- Known pregnancy
- Has taken any probiotics, prebiotics in the last month
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 4 and 17 years old?
Where in Hong Kong
- The Chinese University of Hong KongHong Kong, Hong KongContact: Zhi-xiu Lin, PhDTaking people
About the trial
What the trial wants to find out
The study aims to evaluate the clinical efficacy and safety of the modified Qing-Ying Decoction (mQYD) for the treatment of subacute and chronic atopic dermatitis (AD) in children when compared to the placebo control through examining the clinical symptoms, quality of life, gut microbiome, and Chinese medicine body constitution.
Read full original descriptionShow less
This is a parallel, randomized, placebo-controlled, double-blind clinical trial. Eligible subjects will be randomly allocated to receive oral mQYD granules or it's placebo granules. Subjects will have 12-week of treatment, and then a 4-week follow-up.
The 2 groups in the trial
- Modified Qing-Ying DecoctionTreatment being tested
Herbal granules, twice per day for 12 weeks
- Identical looking placeboPlacebo, for comparison
Placebo granules, twice per day for 12 weeks
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Randomized Placebo-Controlled Clinical Trial of an Innovative Herbal Formula for Atopic Dermatitis in Children: Evaluations of Modified Qing-Ying Decoction on Efficacy and Gut Microbiome
- Plain-language title
- Tests a herbal formula for eczema in children against a placeboGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT04419584, who can take part
- Record updated
- 30 July 2026