Diffusion Basis Spectrum Imaging of the Prostate
Key facts
- Where
- St Louis, United StatesSee the site
Where in United States
- Washington University School of MedicineSt Louis, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Washington University School of Medicine
- Trial code
- NCT04420702
- Record updated
- 9 November 2026
- Original description
Diffusion Basis Spectrum Imaging (DBSI) represents a potential leap forward in improving prostate cancer early detection: a non-invasive and accurate imaging test for clinically significant prostate cancer.Read full original descriptionShow less
Diffusion Basis Spectrum Imaging of the Prostate: A Virtual Biopsy to Accurately Diagnose Prostate Cancer
Diffusion Basis Spectrum Imaging (DBSI) represents a potential leap forward in improving prostate cancer early detection: a non-invasive and accurate imaging test for clinically significant prostate cancer.
Inclusion: Over 18 years of age and willing and able to provide informed consent; Patients with no prior diagnosis of prostate cancer, who are planning to undergo prostate biopsy as clinical standard of care ("early detection cohort"); Including those men with:; an elevated PSA and no prior biopsy; an elevated PSA and a negative prior biopsy; Patients with a prior diagnosis of prostate cancer, who are currently managed with active surveillance, who are planning to undergo biopsy as clinical standard of care ("active surveillance cohort").
Exclusion: Patients with any clinical contraindication to MRI; *Including but not limited to:; Those with metallic implants, such as pacemakers or implantable cardioverter-defibrillators; Those with cochlear implants; Those with claustrophobia not relieved with medications (patients with claustrophobia who do not need medications for the scan or whose claustrophobia can be managed with medication, are eligible to participate); Those who cannot lie flat for over 1 hour; Patients with prior prostate surgery for prostate cancer (e.g. radical prostatectomy, focal ablation).