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A treatment plan for children with retinoblastoma in Africa

Tests a treatment plan for children with retinoblastoma in Africa.

Plain-language title generated from the registry record
Registry title: Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma

Key facts

Where
Bamako, MaliSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for children with retinoblastoma (an eye cancer) that is still inside the eye or has spread only into the eye socket.

Age
Up to 18 years
Sex
Boys and girls
Disease stage
Retinoblastoma in one eye inside the eye, or in one eye inside the eye socket; or in both eyes inside the eye; or inside one eye and in the socket of the other eye.

Main reasons for not taking part

  • Tumour mass that has come out of the eye
  • Large spread along the optic nerve
  • Spread into the brain or its linings, or into the spinal fluid
  • Spread to nearby lymph nodes or to distant parts of the body
  • Trilateral retinoblastoma, or unable to follow the whole treatment

Read by machine on 12 November 2026.

Where in Mali

  • CHU Gabriel Touré (HGT)Bamako, MaliContact: Boubacar TOGO, PROFESSEURTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
French Africa Pediatric Oncology Group
Trial code
NCT04425434
Record updated
2 March 2026
Original description
As the survival of children with retinoblastoma in high income countries is higher than 95% including the bilateral forms this study hopes to improve the outcome in low income countries in Africa by improving early diagnosis and early implementation of this protocol of therapeutic recommendations for treatment.Read full original descriptionShow less

Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma

As the survival of children with retinoblastoma in high income countries is higher than 95% including the bilateral forms this study hopes to improve the outcome in low income countries in Africa by improving early diagnosis and early implementation of this protocol of therapeutic recommendations for treatment.

Inclusion: Unilateral intraocular Retinoblastoma (RB); Unilateral extraocular intraorbital (RB); Bilateral intraocular (RB); bilateral intraocular (RB) on one side and extraocular but intraorbital on the other side.

Exclusion: Externalized tumor mass; massive extension to optic nerve up to optical channeltumor; intracranial extension leptomeninges; cerebral parenchyma; extension to regional lymph nodes and/or remote metastases; cerebrospinal fluid involvement; Trilateral RB; Incapacity to followed the whole treatement.

ClinicalTrials.gov NCT04425434