A treatment plan for children with retinoblastoma in Africa
Tests a treatment plan for children with retinoblastoma in Africa.
Key facts
- Who runs it
- French Africa Pediatric Oncology Group
- Where
- Dakar, SenegalSee the siteAlso in 5 other countries, 6 sites
- Trial code
- Registry title
- Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma
- Status
- Recruiting
- People taking part
- 3,000 people, planned
- Started
- 1 Nov 2020
- Expected to end
- 31 Dec 2030
- Type of study
- Observational
- Treatments tested
- OBSERVATIONAL
- Record updated
- 2 March 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for children with retinoblastoma (an eye cancer) that is still inside the eye or has spread only into the eye socket.
- Age
- Up to 18 years
- Sex
- Boys and girls
- Disease stage
- Retinoblastoma in one eye inside the eye, or in one eye inside the eye socket; or in both eyes inside the eye; or inside one eye and in the socket of the other eye.
Main reasons for not taking part
- Tumour mass that has come out of the eye
- Large spread along the optic nerve
- Spread into the brain or its linings, or into the spinal fluid
- Spread to nearby lymph nodes or to distant parts of the body
- Trilateral retinoblastoma, or unable to follow the whole treatment
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- Unilateral intraocular Retinoblastoma (RB)
- Unilateral extraocular intraorbital (RB)
- Bilateral intraocular (RB)
- bilateral intraocular (RB) on one side and extraocular but intraorbital on the other side
Who cannot take part
- Externalized tumor mass
- massive extension to optic nerve up to optical channeltumor
- intracranial extension leptomeninges
- cerebral parenchyma
- extension to regional lymph nodes and/or remote metastases
- cerebrospinal fluid involvement
- Trilateral RB
- Incapacity to followed the whole treatement
Where in Senegal
Also in 5 other countries, 6 sites
- Hôpital Aristide Le DantecDakar, SenegalContact: Fatou-Binetou DIAGNE AKONDE, DRTaking people
About the trial
What the trial wants to find out
As the survival of children with retinoblastoma in high income countries is higher than 95% including the bilateral forms this study hopes to improve the outcome in low income countries in Africa by improving early diagnosis and early implementation of this protocol of therapeutic recommendations for treatment.
Treatments tested
- OBSERVATIONAL
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma
- Plain-language title
- A treatment plan for children with retinoblastoma in AfricaGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 2 March 2026