Brain Imaging Study Following Babies' Brain Development From Before Birth
Uses MRI scans and behavior checks to track how babies' brains develop.
Key facts
- Who runs it
- King's College London
- Where
- London, United KingdomSee the site
- Trial code
- Registry title
- Brain Imaging in Babies Study
- Status
- Recruiting
- People taking part
- 790 people, planned
- Started
- 5 Apr 2013
- Expected to end
- May 2028
- Type of study
- Observational, 2 groups
- Record updated
- 5 March 2024
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for pregnant mothers, with or without COVID-19, and for babies, with or without a close family history of autism or other neurodevelopmental conditions. Participants must live in England.
- Age
- 16 to 75 years
- Sex
- All
Main reasons for not taking part
- Further screening may exclude some people. The record gives no details.
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Pregnant mothers with and without confirmed COVID-19
- Infants with and without an immediate family history of Autism Spectrum and neurodevelopmental conditions
- Based in England, UK
Who cannot take part
- based on further screening
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 16 and 75 years old?
Where in United Kingdom
- King's College LondonLondon, United KingdomContact: Gráinne McAlonan, PhDTaking people
About the trial
What the trial wants to find out
The aims of the BIBS Study
Read full original descriptionShow less
The Brain Imaging in Babies study (BIBS) aims to improve understanding of how a baby's brain develops from before birth, up until 3-4 years of age. Working with children from a variety of backgrounds and communities, the investigators use a combination of state-of-the-art diagnostic tools such as MRI scans alongside traditional behavioural assessments to capture the earliest information on infant brain development.
The focus of the BIBS study
MRI scanning is a safe way of producing detailed images using strong magnetic fields and radio waves. It does not use X-ray. Along with learning more about brain development in general, the investigators also try to identify features that may in future help predict whether a child will or will not develop traits of conditions such as Autism Spectrum Disorder (ASD) or Attention Deficit Hyperactivity Disorder (ADHD). Long-term, this may help target useful interventions early on, helping children who are most in need.
Since COVID-19 arrived in the United Kingdom (U.K.) in 2020, the investigators have been given ethical approval to include testing for this infection in the mothers and children participating in the study. This may provide an opportunity to better understand how mother and baby respond to infections. The investigators particularly welcome mothers who have had a positive COVID-19 test during their pregnancy to join the study.
The 2 groups in the trial
- Infants a family history of ASD/ADHD
- Infants without a family history of ASD/ADHD
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Brain Imaging and Infant Development
- Plain-language title
- Brain Imaging Study Following Babies' Brain Development From Before BirthGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT04443179, who can take part
- Record updated
- 5 March 2024