Robotic arm training for arm recovery in people with chronic stroke
Compares two robotic training approaches for arm function in adults with chronic stroke.
Plain-language title generated from the registry record
Registry title: Proximal Priority Versus Distal Priority Robotic Priming Effects in Patients With Chronic Stroke
Key facts
- Where
- New Taipei City, Taichung, and Taipei, TaiwanSee the 4 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 20 to 75 who had a first stroke more than 3 months ago and still have moderate to severe weakness in one arm.
- Age
- 20 to 75 years
- Sex
- All
- Disease stage
- More than 3 months after a first stroke on one side of the brain (ischemic or hemorrhagic). Moderate to severe arm motor impairment (Fugl-Meyer Assessment arm score between 18 and 56).
- Earlier treatment
- Must not be taking part in other medication or rehabilitation studies at the same time.
Main reasons for not taking part
- Other neurologic, neuromuscular or orthopedic disease, such as epilepsy
- Severe health or physical conditions that might impede participation
- Severe spasticity (muscle stiffness) in any joint of the affected arm (modified Ashworth Scale score of 3 or more)
- Arm fracture in the past 3 months
- Cannot follow instructions (Mini-Mental State Examination score of 24 or less)
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 75 years old?
Source: NCT04446273, who can take part
Where in Taiwan
- Taipei Tzu Chi HospitalNew Taipei City, TaiwanContact: Wan-Ling Hsu, MSTaking people
- Fongyuan HospitalTaichung, TaiwanContact: Chih-Chieh Kuo, MSTaking people
- National Taiwan University HospitalTaipei, TaiwanContact: Keh-chung Lin, ScDTaking people
- Taipei Municipal Wan Fang HospitalTaipei, TaiwanContact: Han-Ting Tsai, MSTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- National Taiwan University Hospital
- Trial code
- NCT04446273
- Record updated
- 25 February 2026
- Original description
This is a single-blind randomized comparative efficacy study involving 54-72 participants with chronic stroke. Participants will be randomized into proximal priority robotic group or distal priority robotic group and receive 18 intervention sessions (90 min/d, 3 d/wk for 6 weeks). The Fugl-Meyer Assessment Upper Extremity subscale, Medical Research Council Scale, Revised Nottingham Sensory Assessment, and Wolf Motor Function Test will be administered at baseline, after treatment, and at the 3-month follow-up. Two-way repeated-measures analysis of variance and the Chi-Square Automatic Interaction Detector Method will be used to examine the comparative efficacy and predictors of outcome, respectively, after intervention.Read full original descriptionShow less
Effects of Proximal Priority Versus Distal Priority Robotic Priming Technique With Rehabilitation Therapy of Upper-Limb Functions in Patients With Chronic Stroke
This is a single-blind randomized comparative efficacy study involving 54-72 participants with chronic stroke. Participants will be randomized into proximal priority robotic group or distal priority robotic group and receive 18 intervention sessions (90 min/d, 3 d/wk for 6 weeks). The Fugl-Meyer Assessment Upper Extremity subscale, Medical Research Council Scale, Revised Nottingham Sensory Assessment, and Wolf Motor Function Test will be administered at baseline, after treatment, and at the 3-month follow-up. Two-way repeated-measures analysis of variance and the Chi-Square Automatic Interaction Detector Method will be used to examine the comparative efficacy and predictors of outcome, respectively, after intervention.
Inclusion: The inclusion criteria are age between 20 and 75 years old, more than 3 months after the onset of a first unilateral ischemic or hemorrhagic stroke, moderate to severe UE motor impairment (i.e., total UE score of the Fugl-Meyer Assessment [FMA] score between 18 and 56), no severe spasticity in any joints of the affected arm (modified Ashworth Scale score <3 in any of the affected shoulder, elbow, wrist, and fingers), able to follow instructions (Mini-Mental State Examination total score >24), no UE fractures in the past 3 months, and not simultaneously participating in other medication or rehabilitation studies.
Exclusion: The exclusion criteria are other neurologic, neuromuscular, or orthopedic disease, such as epilepsy, or severe health or physical conditions that might impede participation in this study.