Studying distress in women and partners after cervical cancer
Studies why some cervical cancer patients and partners feel lasting psychological distress.
Plain-language title generated from the registry record
Registry title: Distress In CErvical Cancer Patients and Partners
Key facts
- Where
- Breda, Eindhoven, Groningen, Maastricht, Nijmegen, and Utrecht, NetherlandsSee the 6 sites
Where in Netherlands
- AmphiaBreda, NetherlandsTaking people
- Catharina hospitalEindhoven, NetherlandsTaking people
- University Medical Center GroningenGroningen, NetherlandsTaking people
- MUMC+Maastricht, NetherlandsTaking people
- RadboudumcNijmegen, NetherlandsTaking people
- UMC UtrechtUtrecht, NetherlandsTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Comprehensive Cancer Centre The Netherlands
- Trial code
- NCT04475354
- Record updated
- 6 December 2023
- Original description
Rationale: A growing number of cervical cancer patients live years beyond their cancer diagnosis and ultimately survive their disease. Cervical cancer patients report higher levels of psychological distress compared to other (gynecological) cancer types, resulting in physical and psychosocial limitations. The mechanisms explaining why some patients do, and others do not experience persistent psychological distress after cervical cancer remain unclear.Read full original descriptionShow less
Mechanisms Explaining Psychological Distress In CErvical Cancer Patients and Partners (DICE): a Population-based Prospective Study
Rationale: A growing number of cervical cancer patients live years beyond their cancer diagnosis and ultimately survive their disease. Cervical cancer patients report higher levels of psychological distress compared to other (gynecological) cancer types, resulting in physical and psychosocial limitations. The mechanisms explaining why some patients do, and others do not experience persistent psychological distress after cervical cancer remain unclear.
Objective: Gain insight into the mechanisms explaining psychological distress (i.e. anxiety, depression, cancer worry, perceived stress) in a prospective population-based sample of cervical cancer patients. Factors to be studied include characteristics of the individual (demographical and clinical, including comorbidities), characteristics of the environment ((sexual) relationships), biological function (cortisol, melatonin and sex hormone production assessed in scalp hair, inflammation and telomere length assessed in blood, overall quality of life (EORTC QLQ-C30), symptoms (EORTC QLQ-CX24), functional status (physical activity and sleep measured using the Actigraph activity tracker, and food intake measured using the online 'Eetmeter'), and general health perceptions (B-IPQ). The second aim is to assess the impact of cervical cancer on partners' distress (cancer worry, illness perceptions, relationship quality, dyadic coping).
Inclusion: Newly diagnosed with cervical cancer stage I, II or III; >18 years or older; Partner of patient participating in the study; >18 years.
Exclusion: Participants with cognitive impairment will not be included because of expected difficulties in completing the questionnaires without assistance; Participants with cognitive impairment will not be included because of expected difficulties in completing the questionnaires without assistance; Participants who are not able to read or write Dutch will be excluded, as they are not able to complete a Dutch questionnaire; Partners; Participants who are not able to read or write Dutch will be excluded, as they are not able to complete a Dutch questionnaire.
Patients.