NCT04516499Active, not recruiting
Neurofilament Surveillance Project (NSP)
Remote Blood Biomarker Monitoring in Frontotemporal Lobar Degeneration: Neurofilament Surveillance Project (NSP)
Source: ClinicalTrials.gov · Last updated 18 Jun 2026
Brief summary (registry, in English)
This is a biomarker study designed to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) mutations compared to a control group of individuals without known f-FTLD mutations. The NSP is an ancillary study to the ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration" (ALLFTD) study, NCT04363684. More information can be found at https://www.allftd.org/.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 342 (actual)
- First submitted
- 11 Aug 2020
- Start date
- 2 Sept 2020
- Primary completion date
- 28 Feb 2027
- Lead sponsor
- The Bluefield Project to Cure Frontotemporal Dementia
- Diseases
- Frontotemporal dementia
- NCT number
- NCT04516499
What you commit to
- Study type: Observational
- Participants enrolled: 342
- From 2 Sept 2020 to the primary completion date, 28 Feb 2027
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any conditions or circumstances which, in the opinion of the investigator, would not allow participation in the study.
Other
- Any permanent contra-indication to repeated blood draws, such as poor venous access.
Who the study is looking for
- Male or female
- Ages 18-85
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Is enrolled in the longitudinal arm of ALLFTD
- Is a member of a family with a known mutation in C9orf72, GRN or MAPT
Age in the registry: 18 years to 85 years · Sex: All · Accepts healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins University School Of Medicine Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Charlestown | United States | Unknown status |
| Mayo Clinic Florida Coordinator of this site? Confirm its status | Jacksonville | United States | Unknown status |
| Columbia University Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
| Washington University in St. Louis Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.