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Magnetic Stimulation Study for Repetitive Behaviors in Autism

Tests theta-burst magnetic brain stimulation for repetitive behaviors in people with autism.

Plain-language title generated from the registry record
Registry title: Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD

Key facts

Where
Stanford, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 12 and 45 years old?

Source: NCT04532424, who can take part

Where in United States

  • Stanford UniversityStanford, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Stanford University
Trial code
NCT04532424
Record updated
5 November 2026
Original description
Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.Read full original descriptionShow less

Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD

Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.

Inclusion: Diagnosis of Autism Spectrum Disorder (ASD); Meet criteria for Autism Spectrum Disorder (ASD) on clinical assessments (ADOS-2 or CARS if conducted remotely \& ADI-R); Aged between 12-45 years old; Have a reliable informant who can complete relevant questionnaires; Have DARB scores which indicate high levels (50% or above) of RRB on one of the following domains: Insistence on Sameness, Obsessive Compulsive Behaviors, and Unusual Interests.

Exclusion: Any contraindications for TMS e.g. history of seizures other than clear substance-induced/fever-induced seizures with neurologist note or normal clean EEG and no seizure in at least 12 months prior to enrollment; Currently taking Clozapine or another medication that the PI determines increases the risk of TMS or may disrupt the efficacy; Any current or past history of any physical condition which in the investigator's opinion might put the subject at risk or interfere with study results interpretation; DSM-5 diagnosis of bipolar disorder or a psychotic disorder e.g. schizophrenia; Conditions that increase the risk for COVID-19 (in accordance with university guidelines); Pregnancy; Active substance use (<1 week) or intoxication verified by toxicology screen--of cocaine, amphetamines, benzodiazepines; Showing symptoms of withdrawal from alcohol or benzodiazepines; Significant sensory impairments such as blindness or deafness; Current severe insomnia (must sleep a minimum of 4 hours the night before stimulation); Not willing to cooperate with the TMS procedures; A motor threshold that is too high to allow safe/tolerable treatment.

ClinicalTrials.gov NCT04532424