NCT04538976CompletedPhase 4
Copd Exacerbation and Pulmonary Hypertension Trial
Source: ClinicalTrials.gov · Last updated 13 Mar 2025
Brief summary (registry, in English)
This trial will investigate whether patiens admitted with an acute exacerbation of chronic obstructive lung disease and pulmonary hypertension will benefit from a targeted pharmacological treatment.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 250 (actual)
- First submitted
- 30 Aug 2020
- Start date
- 1 Feb 2020
- Primary completion date
- 15 Mar 2024
- Lead sponsor
- Chronic Obstructive Pulmonary Disease Trial Network, Denmark
- NCT number
- NCT04538976
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 250
- From 1 Feb 2020 to the primary completion date, 15 Mar 2024
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known pulmonal hypertension
- Known heart disease which affects the pump function of the heart
- Severe mental illness which significantly complicates cooperation
- known allergy to Sildenafil
Age
- Men \<40 years
- Women \<55 years
- Not-menopauseal women \<55 years (Menopause is defined as no menstruation within 12 months.)
Other
- Severe language difficulties which significantly complicates cooperation
- Sildenafil consumption ≥50 mg / week due to other indications
Who the study is looking for
- COPD verified by specialist and spirometry
- Admitted with the diagnosis "acute exacerbation of COPD"
- TR-gradient ≥40 mmHg verified by specialist and echocardiography
- Informed consent
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Herlev-Gentofte Hospital Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Hvidovre Hospital Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Bispebjerg University Hospital Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Nordsjællands Hospital Coordinator of this site? Confirm its status | Hillerød | Denmark | Unknown status |
| Odense Universitetshospital Coordinator of this site? Confirm its status | Odense | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.