Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe

Prior treatment

• Partcipants with upper respiratory infection at least 7 days prior to the procedure
• Participants currently taking H2 Histamine Antagonists (such as Pepcid, Axid, Tagamet, Zantac, etc)
• Participants currently taking Mast Cell stabilizers

Other illness

• Participants with a history of upper respiratory disease or surgery
• Participants with a history of upper gastrointestinal surgery
• Participants with any contraindications to the placement of the NJ tube including deviated septum or any other anatomical abnormalities of the nasopharynx or upper gastrointestinal region, history of trans-sphenoidal surgery, facial or cranial trauma and fractures, chronic sinusitis, esophageal strictures, varices etc.
• Participants with a history of or being on medications that delay gastric emptying.
• Participants on drugs which impair clotting like anticoagulants and antiplatelet drugs, NSAIDS, history of bleeding disorders.
• Participants using nasal steroids or any steroids for environmental allergies
• Participants with suspected or diagnosed HIV
• Participants with a current or history of Alcoholism
• Participants with uncontrolled Diabetes Mellitus 1 \& Diabetes Mellitus 2

Other

• Participants with a recent use of Antibiotics within the past 4 weeks
• Participants with suspected or diagnosed Hep B or Hep C
• Participants enrolled in clinical trials involving interventions that affect Intestinal Permeability
• Participants currently pregnant.

• Healthy subjects
• Participant must be 18 to 60 years of age
• Participant must be able to consent to the procedure
• Participant must fast (no solid food) for at least 8 hours prior to the procedure