Imaging the esophagus nerves of people with Parkinson's disease
Uses a swallowed imaging capsule to study esophagus nerves in Parkinson's disease.
Plain-language title generated from the registry record
Registry title: Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's Disease
Key facts
- Where
- Boston, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 85 years old?
Source: NCT04566341, who can take part
Where in United States
- Massachusetts General HospitalBoston, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Massachusetts General Hospital
- Trial code
- NCT04566341
- Record updated
- 10 November 2026
- Original description
The goal of this research is to determine (1) the feasibility of tethered capsule OCT esophageal imaging in the Parkinson's Disease population; (2) the morphologic changes in the enteric nervous system of the esophagus in patients with Parkinson's disease.Read full original descriptionShow less
Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's Disease
The goal of this research is to determine (1) the feasibility of tethered capsule OCT esophageal imaging in the Parkinson's Disease population; (2) the morphologic changes in the enteric nervous system of the esophagus in patients with Parkinson's disease.
Inclusion: Idiopathic Parkinson's disease as defined by the United Kingdom PD Society Brain Bank Criteria; Parkinson Disease Hoehn and Yahr stage 2-4; Participants on stable dose of Parkinson Disease medications for at least 4 weeks prior to the study screening; Participants between 40 and 85 years old; Participants who are capable of giving informed consent.
Exclusion: Recent intestinal resection (within the last six months); Prior gastric, esophageal or oropharyngeal surgery; Atypical or secondary Parkinson Disease; Esophageal fistula and/or esophageal strictures with a luminal stricture diameter that is smaller than the diameter of the capsule; Inability to swallow capsules; Pregnancy, according to participant information.