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Tests a defibrillator implant in heart disease patients who survived cardiac arrest

Tests a defibrillator implant in adults with heart disease after cardiac arrest.

Plain-language title generated from the registry record
Registry title: A Danish ICD-study in Patients with Coronary Artery Disease Resuscitated from Ventricular Fibrillation

Key facts

Where
Copenhagen, DenmarkSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with coronary artery disease who survived a cardiac arrest caused by a dangerous heart rhythm (VF/VT) and had full revascularization of their heart arteries. The aim is to see whether an implanted defibrillator (ICD) helps them.

Age
18 years or older
Sex
All sexes can join.
Disease stage
Coronary artery disease with cardiac arrest due to ventricular fibrillation or sustained ventricular tachycardia (VF/VT). Heart pumping function (LVEF) above 35% at discharge.
Earlier treatment
Must have had complete revascularization (PCI, CABG or hybrid coronary revascularization) before the ICD is implanted. Must not have had CABG within the last 3 months before the hospital stay.

Main reasons for not taking part

  • Cardiac arrest from a non-ischemic cause (such as ion channel diseases or non-ischemic cardiomyopathy)
  • CABG within the last 3 months before the hospital stay
  • Life expectancy under 1 year or severe neurologic outcome
  • Unable or unwilling to give informed consent
  • Pregnancy

Read by machine on 12 November 2026.

Where in Denmark

  • Copenhagen University Hospital, RigshospitaletCopenhagen, DenmarkContact: Reza Jabbari, MD, PhDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Copenhagen University Hospital, Rigshospitalet
Trial code
NCT04576130
Record updated
27 January 2025
Original description
DanICD is a randomized, controlled study to with the aim to assess whether there is a benefit of ICD-implantation in patients with coronary artery disease (including acute myocardial infarction), who survive cardiac arrest due to ventricular fibrillation/sustained ventricular tachycardia and undergo revascularization and with an LVEF above 35%.Read full original descriptionShow less

A Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillator in Patients with Coronary Artery Disease Resuscitated from Ventricular Fibrillation Who Receive Complete Revascularization

DanICD is a randomized, controlled study to with the aim to assess whether there is a benefit of ICD-implantation in patients with coronary artery disease (including acute myocardial infarction), who survive cardiac arrest due to ventricular fibrillation/sustained ventricular tachycardia and undergo revascularization and with an LVEF above 35%.

Inclusion: Patients with CAD and cardiac arrest due to VF/VT, where angiogram is performed with complete revascularization (PCI, CABG or hybrid coronary revascularization) before ICD implantation. Unfavorable artery for PCI (i.e., excessive vessel tortuosity or chronic total occlusion) or high-risk invasive treatment is not mandatory in order to achive complete revascularization; Age ≥18 years; LVEF >35% at the time of discharge. The most recent LVEF assessment on which the current medical treatment will be based at the time of entry into the study will be used as baseline LVEF.

Exclusion: Previous CABG within the last 3 months before index hospitalization; Non-ischemic cause of cardiac arrest (i.e. ion channel diseases, non-ischemic cardiomyopathy); Life expectancy less than 1 year or severe neurologic outcome; Unable or unwilling to give informed consent; Pregnancy.

ClinicalTrials.gov NCT04576130