Lung ultrasound to check for rejection in people after lung transplant
Tests lung ultrasound for ruling out rejection in adults after lung transplant.
Key facts
- Who runs it
- Mayo Clinic
- Where
- Jacksonville, United StatesSee the site
- Trial code
- Registry title
- Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Lung Transplant Recipients
- Status
- Recruiting
- People taking part
- 90 people, planned
- Started
- 28 Oct 2020
- Expected to end
- 30 Dec 2026
- Type of study
- Interventional
- Treatments tested
- Lung ultrasound
- Record updated
- 5 February 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who have had a lung transplant and have no symptoms. It tests lung ultrasound as a safe, non-invasive way to find rejection and infection.
- Age
- Over 18 years.
- Sex
- All sexes can join.
- Disease stage
- People who have had a single lung, double lung or heart-lung transplant. They must have no symptoms, a clear chest X-ray over the transplanted lung, and normal breathing tests (FEV1 not dropped more than 10% from baseline).
- Earlier treatment
- Must have had a single lung, double lung or heart-lung transplant.
Main reasons for not taking part
- Unable to give consent for the procedure
- Air trapped under the skin (subcutaneous emphysema)
- Other technical problems that, in the operator's view, could stop clear ultrasound images
This trial only enrols participants who have had an organ transplant. The registry sentence this rests on: * Adult patients (> 18 yrs) who had undergone single/double/heart-lung transplant
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Adult patients (> 18 yrs) who had undergone single/double/heart-lung transplant
- Asymptomatic
- Normal spirometry defined as a FEV1 without significant drop from baseline (significant drop = >10% decrease from baseline)
- Clear chest radiograph over allograft
Who cannot take part
- Patients who are unable to consent for the procedure
- Patients with subcutaneous emphysema or other technical challenges that could interfere with satisfactory image acquisition- as deemed by the operator
Where in United States
- Mayo Clinic in FloridaJacksonville, United StatesContact: Neha ShuklaTaking people
About the trial
What the trial wants to find out
This study is being done to study a safe and non-invasive way to diagnose lung rejection and infection.
The group in the trial
- Receiving UltrasoundTreatment being tested
Every patient will receive a lung ultrasound prior to each scheduled bronchoscopy until the study stops.
Treatment: Lung ultrasound
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Application of Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Asymptomatic Lung Transplant Recipients
- Plain-language title
- Lung ultrasound to check for rejection in people after lung transplantGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Record updated
- 5 February 2026