Frontlight ResearchEarly access
CompletedNo phase
Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery
Key facts
- Who runs it
- University Hospital, Basel, Switzerland
- Where
- Switzerland1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 54 people enrolled
- Started
- 22 Jan 2021
- Ended
- 29 Jun 2024
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Endonasal endoscopic pituitary surgery in semi-sitting position
- Endonasal endoscopic pituitary surgery in supine position
- Record updated
- 29 April 2025
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Patients with a presumed pituitary pathologies who are suitable for endoscopic endonasal surgical resection
Who cannot take part
- Patients with known hemorrhagic or thrombophilic disorders
- Patients with conditions associated with high central venous pressure: congestive heart failure, pulmonary hypertension, chronic obstructive pulmonary disease (COPD), interstitial lung disease, pregnancy
- Patients with poor cardiopulmonary condition (unable to perform 4 metabolic equivalents without stopping (climb a flight of stairs))
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
This study is to prospectively compare the standard supine (control group) and the semi-sitting position (head elevation of 30°; intervention group) in endoscopic endonasal pituitary surgery.
The 2 groups in the trial
- Study InterventionExisting treatment, for comparison
Endonasal endoscopic pituitary surgery in semi-sitting position
Treatment: Endonasal endoscopic pituitary surgery in semi-sitting position
- Control InterventionExisting treatment, for comparison
Endonasal endoscopic pituitary surgery in supine position
Treatment: Endonasal endoscopic pituitary surgery in supine position
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery (PosESS-Study) - Study Protocol for a Randomized-controlled Single-blinded Superiority Trial
- Record updated
- 29 April 2025