Studies brain immune cell activity and lesion growth in multiple sclerosis
Observes whether immune cell activity at brain lesion edges relates to lesion growth.
Plain-language title generated from the registry record
Registry title: Does Microglial Activation Promote Lesion Growth and Progression Among Multiple Sclerosis Patients
Key facts
- Where
- Turku, FinlandSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 30 and 80 years old?
Source: NCT04625049, who can take part
Where in Finland
- Turku PET CentreTurku, FinlandNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Turku University Hospital
- Trial code
- NCT04625049
- Record updated
- 22 September 2025
- Original description
The purpose of this study is to assess whether increased microglial activation (measured using TSPO-PET) at lesion rim is associated with more rapid lesion growth during 10 year follow up.Read full original descriptionShow less
Does Microglial Activation Promote Lesion Growth and Progression Among Multiple Sclerosis Patients
The purpose of this study is to assess whether increased microglial activation (measured using TSPO-PET) at lesion rim is associated with more rapid lesion growth during 10 year follow up.
Inclusion: Participation to a previous PET imaging study of Airas group; MS diagnosis.
Exclusion: Patients with other neurodegenerative disease than MS; Patients with claustrophobia, or a history of moderate to severe anxiety disorder or panic attacks (which could potentially lead to preterm termination of the imaging); Contraindication to MR scan investigations.